Search for dissertations about: "neutrophil motility"

Showing result 1 - 5 of 8 swedish dissertations containing the words neutrophil motility.

2. 1. Towards a Refined Model of Neutrophil Motility

   Author : Vesa-Matti Loitto; Karl-Eric Magnusson; Tommy Andersson; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human polymorphonuclear leukocytes. PMNL; neutrophils; neutrophil motility; N-formyl-Met-Leu-Phe; Medical microbiology; Medicinsk mikrobiologi;

   Abstract : The ability of human polymorphonuclear leukocytes (PMNL; neutrophils), to sense and move to sites of infection is essential for our defense against pathogens. Cell motility is critically dependent on a dynamic remodeling of morphology. READ MORE

4. 2. Signaling capacity of ß2-integrins in relations to neutrophil motility

   Author : Ragnhild Löfgren; Linköpings universitet; []
   Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; INTERDISCIPLINARY RESEARCH AREAS; TVÄRVETENSKAPLIGA FORSKNINGSOMRÅDEN;

   Abstract : The neutrophil granulocyte is one of the most mobile cell types in the human body and represents the first line of defense against invading pathogens. Adhesion and chemotactic receptors on the cell surface work together through modulations of the cytoskeleton and thereby cause the cell to move. READ MORE

5. 3. Functions of integrin receptors in extravascular neutrophil migration and respiratory burst

   Author : Joachim Werr; Karolinska Institutet; Karolinska Institutet; []
   Keywords : adhesion molecules; leukocyte migration; neutrophils; chemotaxis; integrins; respiratory burst; leukocyte extravasation; extracellular matrix; intravital microscopy; acute inflammation;

   Abstract : Leukocytes circulate in the vasculature, but, must leave the blood stream and migrate through the surrounding tissue to exert their protective functions in inflammation. Numerous studies have revealed that intravascular leukocyte-endothelial cell interactions involve functions of adhesion molecules belonging to the selectin and integrin receptor families. READ MORE

6. 4. Obesity, Adipocytes and Breast Cancer – Insights from Translational Studies

   Author : Malin Bergqvist; Bröstcancer - prevention & intervention; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast Cancer; Breast cancer risk; Breast cancer prognosis; Obesity; Adipocyte; Adipokines; CAP; Neutrophil to lymphocyte ratio;

   Abstract : Background: Being overweight is becoming the new normal, and more than half of the adult Swedish population is overweight which poses a risk to public health. Overweight and obese women have both an increased risk and a worse prognosis for breast cancer, compared with women of normal weight. READ MORE

7. 5. Nitric oxide and evaluation of different treatments in experimental colitis and inflammatory bowel disease

   Author : Sofie Lundberg; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), is a chronic inflammatory disorder of unknown etiology of the gastrointestinal tract. Central features of IBD are increased nitric oxide (NO) generation in the gut lumen and dysfunction in regulation of leukocyte recruitment from the blood stream towards the affected tissue. READ MORE