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Showing result 11 - 15 of 398 swedish dissertations matching the above criteria.

2. 11. Neutrophil Chemotaxis and Respiratory Burst in Term and Preterm Newborn Infants

   Author : Maria Stålhammar; Richard Sindelar; Jens Schollin; Uppsala universitet; []
   Keywords : innate immunity; neutrophil; term newborn infants; preterm newborn infants; chemotaxis; respiratory burst; reactive oxygen species; cell surface receptor; IL-8; bacterial N-formyl peptide;

   Abstract : Neutrophil activation is the most important initial immune defense against invading microbes in newborn infants. The reduced neutrophil migration and uncontrolled regulation of reactive oxygen species (ROS) production observed in neonates, could result in a diminished infectious response or in tissue damage. READ MORE

4. 12. Studies on Cytotoxic and Neutrophil Challenging Polypeptides and Cardiac Glycosides of Plant Origin

   Author : Senia Johansson; Tore Mellstrand; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; cytotoxic; neutrophil; polypeptides; Phoradendron tomentosum; Digitalis purpurea; plant; mistletoe; MS MS; Edman degradation; breast cancer; macrocyclic peptides; multidrug resistance protein; primary structures; phoratoxin; isolation; digitoxin; cardiac lycoside; structure-activity; Farmaceutisk kemi; Pharmaceutical chemistry; Farmaceutisk kemi; Pharmacognosy; farmakognosi;

   Abstract : This thesis examines the isolation and characterisation (biological and chemical) of polypeptides from plants. A fractionation protocol was developed and applied on 100 plant materials with the aim of isolating highly purified polypeptide fractions from small amounts of plant materials. READ MORE

5. 13. The role of the epithelial cell in Escherichia coli induced neutrophil migration into the urinary tract

   Author : William Agace; Slemhinnans immunologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; E.coli; cytokines; epithelial cell; mucosal inflammation; neutrophil; serology; transplantation; Immunologi; serologi;

   Abstract : This study examined the molecular mechanisms of neutrophil migration to sites of mucosal bacterial infection. (1) Bacterial induction of neutrophil chemotactic cytokines and their role in neutrophil migration. Uropathogenic E. READ MORE

6. 14. Intracellular radicals in neutrophils - processing and functional implications

   Author : Halla Björnsdottir; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neutrophil; reactive oxygen species; neutrophil extracellular traps;

   Abstract : Neutrophils are the most abundant leukocyte in human blood and essential components of our defense against microbial pathogens. These cells can neutralize microbial pathogens by phagocytosis, which involves engulfment and degradation of microbes intracellularly, as well as by the formation of neutrophil extracellular traps (NETs), which are structures released from neutrophils made up of DNA and proteins that capture microbes extracellularly. READ MORE

7. 15. Imaging and Spectroscopic Mapping of Blood Cell Activity : Nanoparticles and Neutrophil Extracellular Traps

   Author : Kalle Bunnfors; Kajsa Uvdal; Caroline Brommesson; Christelle Prinz; Linköpings universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Neutrophils; Neutrophil extracellular traps; fluorescence; XPS; TEM;

   Abstract : Imaging and visualization of cell activity when exposed to nanomaterial are of main importance, when investigating biological response to a wide range of biomaterials from medical implants to smart nanoprobes. The ability to provide molecular and chemical information with spatial resolution in the region of sub-µm leads to increased insight and understanding of these biological challenges. READ MORE