Search for dissertations about: "next generation analysis"
Showing result 1 - 5 of 242 swedish dissertations containing the words next generation analysis.
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1. Mitochondrial Genome Analysis Using Next Generation Sequencing for Forensic Applications
Abstract : Mitochondrial DNA (mtDNA) analysis plays a specialized role in forensic applications, overcoming certain limitations of autosomal DNA markers. The high copy number and uniparental inheritance pattern of mtDNA are advantageous in cases involving shed hairs and aged skeletal elements, especially decades-old missing persons cases. READ MORE
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2. Next generation molecular diagnostics using ultrasensitive sequencing
Abstract : Massively parallel sequencing enables the exploration of the genetic heterogeneity within microbial, viral and tumor cell populations. Detecting circulating tumor DNA in blood and other body fluids has the potential to revolutionize molecular diagnostics. READ MORE
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3. Securing the Next Generation Web
Abstract : With the ever-increasing digitalization of society, the need for secure systems is growing. While some security features, like HTTPS, are popular, securing web applications, and the clients we use to interact with them remains difficult. To secure web applications we focus on both the client-side and server-side. READ MORE
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4. Proximity Ligation Assays for Disease Biomarkers Analysis
Abstract : One of the pressing needs in the field of disease biomarker discovery is new technologies that could allow high performance protein analysis in different types of clinical material, such as blood and solid tissues. This thesis includes four approaches that address important limitations of current technologies, thus enabling highly sensitive, specific and parallel protein measurements. READ MORE
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5. Towards a New Generation of Anti-HIV Drugs : Interaction Kinetic Analysis of Enzyme Inhibitors Using SPR-biosensors
Abstract : As of today, there are 25 drugs approved for the treatment of HIV and AIDS. Nevertheless, HIV continues to infect and kill millions of people every year. Despite intensive research efforts, both a vaccine and a cure remain elusive and the long term efficacy of existing drugs is limited by the development of resistant HIV strains. READ MORE