Search for dissertations about: "nicotinic acid"
Showing result 1 - 5 of 25 swedish dissertations containing the words nicotinic acid.
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1. Modelling of tolerance and rebound in normal and diseased rats
Abstract : The development of rebound and tolerance is an important consideration when optimizing medical therapy, both with respect to drug dosing and adverse effects. By using quantitative approaches to study these processes, potential risks can be minimized. READ MORE
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2. Conditional and non-conditional reward-related responses to alcohol. Nicotinic mechanisms
Abstract : The mesolimbic dopamine system is believed to mediate the positive reinforcing and rewarding effects of addictive drugs by increasing dopamine levels in its terminal area, the nucleus accumbens (nAc). Nicotinic acetylcholine receptors (nAChRs) within this system appear important for the pharmacological actions of both alcohol and nicotine, which may explain the frequent co-abuse of these two drugs. READ MORE
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3. Studies on potential hypolipidemic agents : synthesis and biological evaluation of aryloxyacetic acid derivatives, pro-drugs of nicotinic acid and aliphatic aminoalcohols
Abstract : .... READ MORE
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4. Optimizing nicotinic acid delivery for durable antilipolysis and improved metabolic control
Abstract : Type 2 diabetes is a devastating disease affecting hundreds of millions worldwide. Lipid accumulation in peripheral non-adipose tissues is a major driver of insulin resistance, a central pathophysiological defect of this disease. READ MORE
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5. Lipolysis in rabbit, dog and human adipose tissue : effects of noradrenaline, ACTH, theophylline, nicotinic acid, prostaglandin E1 and age
Abstract : .... READ MORE