Search for dissertations about: "nicotinic receptor antibodies"

Showing result 1 - 5 of 8 swedish dissertations containing the words nicotinic receptor antibodies.

  1. 1. Pamoplantar Pustulosis. Pathogenetic Studies with Special Reference to the Role of Nicotine

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Eva Hagforsen; [2001]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medical sciences; Palmoplantar pustulosis; smoking; sweat gland apparatus; neuropeptides; non-neuronal cholinergic system; nicotinic receptor antibodies; autoimmune disease; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Dermatology and Venerology; dermatologi och venereologi;

    Abstract : Palmoplantar pustulosis (PPP) is a chronic disease of unknown pathogenesis. Most of the patients were smokers. High prevalence of a number of autoimmune diseases was observed among the patients (thyroid disease 14%, gluten intolerance 8%, diabetes type 1 3%).Eosinophils and neutrophils were found in large numbers in the pustules. READ MORE

  2. 2. Molecular mechanisms of HLA associations with myasthenia gravis

    University dissertation from Stockholm : Karolinska Institutet, false

    Author : Peter Hjelmström; Karolinska Institutet.; Karolinska Institutet.; [1997]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Myasthenia gravis; MHC; HLA; T cell receptor; acetylcholine receptor; TNF-a; thymus complex disease trait; autoimmunity; molecular modelling; stratification; DNA polymorphisms;

    Abstract : Myasthenia gravis (MG) is a neuromuscular disease characterised by muscle weakness due to an autoimmune attack against the nicotinic acetylcholine receptor (nAChR). MG has a complex pattem of inheritance and several genetic and environmental factors are important in conferring susceptibility to the disease. READ MORE

  3. 3. Genetic and immunological control of human myasthenia gravis

    University dissertation from Stockholm : Karolinska Institutet, Department of Medicine

    Author : Xiaoyan Zhao; Karolinska Institutet.; Karolinska Institutet.; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Myasthenia Gravis MG ; beta2-adrenergic receptor beta2-AR ; CCR2; CCR5; cytolytic T lymphocyte-associated antigen-4 CTLA-4 ; OX40;

    Abstract : Myasthenia gravis (MG) is a classical autoimmune disease characterized by muscle weakness due to an immune attack against the nicotinic acetylcholine receptor (AChR) on the post-synaptic membrane of the neuromuscular junction. Because of the involvement of multiple factors in the disease, the overall aims of this thesis were to uncover the regulation of candidate genes and the possible cellular mechanisms involved in the immuno-regulation of human MG. READ MORE

  4. 4. CTLA-4 expression, regulation and associations in autoimmune myasthenia gravis

    University dissertation from Stockholm : Karolinska Institutet, Department of Medicine

    Author : XiongBiao Wang; Karolinska Institutet.; Karolinska Institutet.; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cytotoxic-T-lymphocyte-associated antigen 4 CTLA-4 ; Myasthenia gravis MG ; Immune inhibitory receptor; Autoimmune disease; Genetic polymorphism.;

    Abstract : Myasthenia gravis (MG) is a neuromuscular disease with muscle weakness due to an autoimmune attack against the nicotinic acetylcholine receptor (nAChR) on the skeletal muscle endplate. Cytotoxic-T-lymphocyte-associated antigen 4 (CTLA-4) plays a global inhibitory role in the immune system and has a crucial role in autoimmunity. READ MORE

  5. 5. Immunochemical, biochemical and evolutionary studies on Micrurus nigrocinctus nigrocinctus venom toxins

    University dissertation from Stockholm : Karolinska Institutet, false

    Author : Alberto Alape-Girón; Karolinska Institutet.; Karolinska Institutet.; [1997]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Monoclonal antibody; Phospholipase A2; neurotoxin; myotoxin; protein evolution;

    Abstract : Immunochemical, biochemical and evolutionary studies on Micrurus nigrocinctus nigrocinctus venom toxins Monoclonal antibodies (MAbs) were produced against venom proteins of M. nigrocinctus nigrocinctus, the medically most important elapid of Central America. READ MORE