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Showing result 1 - 5 of 66 swedish dissertations matching the above criteria.
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1. Nicotinic and muscarinic receptors in Alzheimer's disease : studies of receptor subtype impairments and modulation by cholinesterase inhibitors and nicotinic agonists
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2. Nicotinic receptors in the central nervous system : methodological and functional aspects
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3. Evolution of acetylcholine receptors and study of the anatomy of the mouse brain reward system
Abstract : This thesis work is divided in two parts. In the first part, I make use of the transgenic TRPV1-Cre mouse line as a tool to investigate the midbrain ventral tegmental area (VTA). READ MORE
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4. Development of nicotinic receptor ligands for positron emission tomography - from in vitro to in vivo : Binding studies of neuronal nicotinic acetylcholine receptors using different ³H-, ¹1C- and `6Br - labeled ligands
Abstract : Neuronal nicotinic acetylcholine receptors (nAChRs) are involved in central processes, such as cognitive functionand memory, and play a critical role in neuropathological changes in Alzheimer's disease (AD). The in vivocharacterization of nAChRs by positron emission tomography (PET) may increase our understanding of thefunctional implications of these receptors in AD and their early changes during this disease. READ MORE
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5. Neurotoxic Effects of Nicotine During Neonatal Brain Development : Critical Period and Adult Susceptibility
Abstract : This thesis examined neurotoxic effects of nicotine exposure during a defined critical period of neonatal brain development in mice.In our environment there are numerous hazardous contaminants that an individual can be exposed to during its entire lifetime. READ MORE