Search for dissertations about: "nitric oxide aorta"

Showing result 1 - 5 of 10 swedish dissertations containing the words nitric oxide aorta.

2. 1. Vascular actions of antimicrobial peptides

   Author : Cristina Ciornei; Sektion II; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kardiovaskulära systemet; Cardiovascular system; vascular smooth muscle; sepsis; nitric oxide; human antimicrobial peptide LL-37; Antimicrobial peptides; lipopolysaccharide; bactericidal permeability-increasing protein;

   Abstract : The present thesis focuses on the vascular effects of antimicrobial peptides especially mechanisms involving the vasodilator nitric oxide (NO), which is released from the blood vessel wall during inflammatory conditions such as sepsis. Bacterial lipopolysaccharide stimulates the expression of nitric oxide synthase (iNOS), which increases the NO production in vascular tissues or cultured vascular smooth muscle cells (VSMC). READ MORE

4. 2. Studies on vasoactivity of fibrin(ogen) derived peptides

   Author : Katarina Saldeen; Asrar Malik; Linköpings universitet; []
   Keywords : Fibrin ogen derived peptides; vasoactivity; prostacyclin; nitric oxide; angiotensin converting enzyme; MEDICINE; MEDICIN;

   Abstract : Fibrin accumulation is a common fmding in many pathological conditions, such as in inflammatory processes, e.g. in the lungs in pneumonia or pulmonary insufficiency after sepsis. During lysis of the fibrin by plasmin or leukocyte elastase, peptides are released that may contribute to the pathophysiological changes. READ MORE

5. 3. Endothelium-derived substances and regional hemodynamics in experimental hypertension

   Author : Sven-Olof Granstam; Uppsala universitet; []
   Keywords : Medical sciences; nitric oxide; endothelin; hypertension; rats; SHR; hemodynamics; blood pressure; blood flow; acetylcholine; carvedilol; microsphere method; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

   Abstract : The spontaneously hypertensive rat (SHR), a model for experimental hypertension, is considered to have similarities with essential hypertension in humans. Differences between SHR and normotensive Wistar Kyoto rats (WKY) in the vascular response to endothelial-derived substances such as nitric oxide (NO) have been intensively studied in vitro. READ MORE

6. 4. The interplay between the endocrine and cardiovascular systems. A study of the hormonal influence on cardiovascular function and endothelial nitric oxide synthase (eNOS) expression

   Author : Anna Wickman; Göteborgs universitet; []
   Keywords : hypophysectomy · growth hormone · insulin-like growth factor-I · estrogen · vascular reactivity · endothelial function · endothelial nitric oxide synthase · nitric oxide · cardiovascular function · vasculature · kidney · hypertension;

   Abstract : During the present thesis, special interest was focused on the cardiovascular effects of growth hormone (GH) and estrogen (E2) and combined treatment of GH+E2, in particular the possible effects on endothelial nitric oxide synthase (eNOS) expression and nitric oxide (NO) bioavailability for maintaining cardiovascular homeostasis. The possible role of fluid mechanical force e. READ MORE

7. 5. Actions of Antimicrobial Peptides and Bacterial Components in Inflammation

   Author : Thorgerdur Sigurdardottir; Anestesiologi och intensivvård; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sepsis; LL-37; M1 protein; S. pyogenes; Toll-like receptors; phenylephrine; nitr1c oxide; antimicrobial peptides;

   Abstract : Antimicrobial peptides are evolutionally ancient parts of the innate immune system and their primary role is to protect us from infections. The human cathelicidin-derived antimicrobial peptide, LL-37, not only possesses broad spectrum antimicrobial activities but is also able to bind and neutralize bacterial lipopolysaccharide (LPS), an important trigger of the widespread inflammatory response contributing to septic shock. READ MORE