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Showing result 1 - 5 of 358 swedish dissertations matching the above criteria.

  2. 1. Molecular Interactions Studied by Electrophoretic and Diffusion NMR

    Author : Fredrik Hallberg; Peter Stilbs; István Furó; Gareth Morris; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Physical chemistry; NMR; electrophoretic NMR; Ion pairing; complexation; association; diffusion; pulsed field gradient; Nafion; Spectroscopy; Spektroskopi;

    Abstract : Even though electrophoretic NMR (eNMR) experiments may provide unique chemical information and have been performed for three decades, the technique is still rarely applied, mainly because several experimental sources of artifacts have to be controlled to achieve accurate results. In this thesis, new experimental setups and protocols for accurate and precise eNMR experiments are presented. READ MORE

  4. 2. Exploring the structure of oligo- and polysaccharides : Synthesis and NMR spectroscopy studies

    Author : Hanna Jonsson; Göran Widmalm; Antonio Molinaro; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Carbohydrates; NMR spectroscopy; synthesis; lipopolysaccharides; conformational studies; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

    Abstract : A deeper understanding of the diversity of carbohydrates and the many applications of oligo- and polysaccharides found in nature are of high interest. Many of the processes involving carbohydrates affect our everyday life. This thesis is based on six papers all contributing to an extended perspective of carbohydrate property and functionality. READ MORE

  5. 3. Conformations of Flexible Oligosaccharides : Molecular Simulations and NMR spectroscopy

    Author : Robert Pendrill; Göran Widmalm; Jens Duus; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Carbohydrates; Oligosaccharide; Conformation; NMR spectroscopy; MD simulations; organisk kemi; Organic Chemistry;

    Abstract : The conformational preferences of several oligosaccharides are investigated herein using a combination of NMR spectroscopy and molecular dynamics (MD) simulations, focusing on the torsion angles associated with the glycosidic linkages.Strategies for obtaining usable J-HMBC spectra for carbons with an adjacent 13C label are described. READ MORE

  6. 4. Characterizing Chromatography Media : NMR-based Approaches

    Author : Fredrik Elwinger; István Furó; Stéphane Viel; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; chromatography; nuclear magnetic resonance; NMR; self-diffusion; magic-angle spinning; quantitative; distribution coefficient; pore size; Kemi; Chemistry;

    Abstract : Liquid chromatography is an essential technique in manufacturing biopharmaceuticals where it is used on all scales from analytical applications in R&D to full-scale production. In chromatography the target molecule, typically a protein, is separated and purified from other components and contaminants. READ MORE

  7. 5. Structure, dynamics and reactivity of carbohydrates : NMR spectroscopic studies

    Author : Jerk Rönnols; Göran Widmalm; Mikael Bols; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Carbohydrates; Conformation; NMR spectroscopy; Hydrogen bond; organisk kemi; Organic Chemistry;

    Abstract : The main focus of this thesis is on the ring conformations of carbohydrate molecules; how the conformational equilibria and the rates of the associated interconversions are affected by the molecular constitution and their surroundings.The conformational equilibria of a group of amine linked pseudodisaccharides, designed as potential glycosidase inhibitors, comprising α-D-altrosides are described in Chapter 3. READ MORE