Search for dissertations about: "non- human primate"

Showing result 1 - 5 of 26 swedish dissertations containing the words non- human primate.

  1. 1. Analysis of Nucleotide Variations in Non-human Primates

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Ann-Charlotte Rönn; Uppsala universitet.; [2007]
    Keywords : Molecular genetics; SNP; genotyping; primate; chimpanzee; whole genome amplification; multiple displacement amplification; minisequencing; microarray; Y-chromosome; mitochondria; Genetik;

    Abstract : Many of our closest relatives, the primates, are endangered and could be extinct in a near future. To increase the knowledge of non-human primate genomes, and at the same time acquire information on our own genomic evolution, studies using high-throughput technologies are applied, which raises the demand for large amounts of high quality DNA. READ MORE

  2. 2. The non-human primate as a model of human Parkinsonism

    University dissertation from Stockholm : Karolinska Institutet, Biosciences and Nutrition

    Author : Alison McCormack; Karolinska Institutet.; Karolinska Institutet.; [2006]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson s disease; substantia nigra; aging; neuromelanin; MPTP; alpha-synuclein; levodopa; dyskinesia; methamphetamine;

    Abstract : The motor deficits seen in Parkinson s disease (PD) are the result of a loss of catecholaminergic neurons from the substantia nigra (SN) and the associated loss of striatal dopamine. Clinical signs become evident once striatal dopamine levels decline by at least 70-80% and nigral cell numbers by 40%, and worsen with increased duration of the disease. READ MORE

  3. 3. Assessment of Dopamine and Serotonin Release in the Non-Human Primate Brain using PET

    University dissertation from Stockholm : Karolinska Institutet, Dept of Clinical Neuroscience

    Author : Sjoerd J. Finnema; Karolinska Institutet.; Karolinska Institutet.; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The molecular imaging technique positron emission tomography (PET) allows for non-invasive examination of biochemical markers in the living brain. For over three decades PET studies have provided important insight into the relationship of monoaminergic neurotransmitter systems to brain functioning and psychiatric disorders. READ MORE

  4. 4. Receptor use of primate lentiviruses

    University dissertation from Stockholm : Karolinska Institutet, Microbiology and Tumor Biology Center (MTC)

    Author : Dalma Vödrös; Karolinska Institutet.; Karolinska Institutet.; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV; SIV; animal models; receptor use; neutralizing antibodies; CD4-independence;

    Abstract : Human and simian immunodeficiency viruses (HIV and SIV) enter target cells using CD4, the primary cell surface receptor and a secondary receptor, called coreceptor. Coreceptor use of HIV can be related to other biological features of the virus and to the severity of infection as well. READ MORE

  5. 5. The role of virus neutralization in primate lentivirus pathogenesis

    University dissertation from Stockholm : Karolinska Institutet, false

    Author : Yi jun Zhang; Karolinska Institutet.; Karolinska Institutet.; [1997]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The antiviral neutralizing activity of sera from primate lentivirus-infected human and monkey hosts was studied. In addition, factors affecting the neutralization reaction were investigated. In simian immunodeficiency virus (SIVsm)-infected macaque monkeys, SIVsm variants able to escape neutralization emerged regularly. READ MORE