Search for dissertations about: "non-obese diabetic NOD"
Showing result 1 - 5 of 22 swedish dissertations containing the words non-obese diabetic NOD.
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1. Metab-Immune analysis of the non-obese diabetic mouse
Abstract : Type 1A diabetes mellitus or T1D is a chronic disease characterized by T cell mediated destruction of the insulin producing β cells in the islets of Langerhans. The classical symptoms include high glucose levels in urine and blood, polyuria, and polydipsia. READ MORE
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2. Cellular and genetic components in the development of IDDM in NOD mice
Abstract : .... READ MORE
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3. Molecular and cellular mechanisms in the development of IDDM in non-obese diabetic mice
Abstract : Insulin dependent diabetes mellitus (IDDM) is a disease caused by autoimmune destruction of the insulin producing b cells in the pancreas. The leukocytic infiltration into the b cell islets preceding disease is called insulitis. READ MORE
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4. B cell repertoire development in normal physiology and autoimmune disease
Abstract : The B cell repertoire in the neonatal immune system (IS) is characterised by reactivity towards self-components, including other immunoglobulin (Ig) V-regions. These properties have been suggested to be a requirement for the development of a normal immune system. READ MORE
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5. Aspects of the glomerular barrier in healthy and diabetic kidneys
Abstract : Each day 180 liters of plasma is filtered in the kidneys. Under normal conditions, the glomerular barrier restricts the passage of macromolecules such as albumin while it is highly permeable to water and small solutes. Proteinuria is a hallmark of renal disease and reflects impairment of the glomerular barrier. READ MORE