Search for dissertations about: "normal tissue"

Showing result 1 - 5 of 1052 swedish dissertations containing the words normal tissue.

  1. 1. Tumor instructed normal tissue : studies of potential extratumoral biomarkers and therapeutic targets in prostate cancer

    Author : Maria Nilsson; Sofia Halin Bergström; Anders Bergh; Kristian Pietras; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; biomarkers; tumor-instructed normal tissue; extra cellular matrix; macrophages; LOX; HO-1; MSMB; Pathology; patologi;

    Abstract : Prostate cancer is the most common cancer in men in Sweden and but luckily the majority of the patients will carry on their life without any consequences from the disease. Unfortunately, some will develop aggressive tumors and eventually die. READ MORE

  2. 2. Tissue Perfusion and Oxygenation Evaluated by Measurements of Tissue Gases and pH. An Experiemental Study

    Author : Åke Mellström; Anestesiologi och intensivvård; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; intensive care; Anestesiologi; intensivvård; Anaesthesiology; Tissue pH; Tissue PCO2; Oxygen utilization; Tissue PO2;

    Abstract : Optimum peripheral perfusion, oxygenation and oxygen utilization is a prerequisite for normal wound healing, resistance to infection and cardiac function. The purpose of this study was to evaluate peripheral oxygen utilization by measurements of subcutaneous tissue gases and pH (PscO2, PscCO2 and pHsc) in comparison to established techniques for measurements of periph-eral tissue oxygenation and oxygen utilization in experimental animal models with hyperoxia-hypoxia, acidosis-alkalosis and haemorrhage-resuscitation. READ MORE

  3. 3. TINT Tumor Indicating Normal Tissue : new field of diagnostic biomarkers for prostate cancer

    Author : Hanibal Hani Adamo; Anders Bergh; Göran Landberg; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostate cancer; biomarkers; TINT; patologi; Pathology;

    Abstract : Background: Prostate cancer is the most common cancer in Sweden. Due its highly variable behavior, multifocal nature, and insufficient diagnostic methods, prostate cancer is difficult to diagnose and prognosticate. READ MORE

  4. 4. Evaluation of Myocardial Function in Chronic Kidney Disease : A Colour Tissue Velocity Imaging Study

    Author : Shirley Hayashi; Lars-Åke Brodin; Svend Aakhus; KTH; []
    Keywords : Cardiac; Kidney; Tissue; Velocity; MEDICINE; MEDICIN;

    Abstract : In patients with chronic kidney disease (CKD), overhydration, uremic toxins and left ventricular (LV) dyssynchrony are factors that may lead to LV dysfunction and conduction abnormalities and thus contribute to the high cardiac mortality. Colour tissue velocity imaging (TVI) allows a detailed quantitative analysis of cardiac function in CKD patients, opening new possibilities to evaluate longitudinal myocardial motion, rapid isovolumetric events, LV filling pressure and LV synchronicity. READ MORE

  5. 5. Small-Scale Absorbed Dose Modelling in Selective Internal Radiation Therapy : Microsphere Distribution in Normal Liver Tissue

    Author : Jonas Högberg; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; clusters; dosimetry; heterogeneity; liver; microspheres; radioembolisation; simulations; SIRT; surgery; yttrium-90;

    Abstract : Radioembolisation (RE), with yttrium-90 (90Y) labelled microspheres, is an increasingly common treatment method for unresectable liver tumours. The tolerable mean absorbed dose for normal liver (NL) tissue is higher in RE than in External Beam Radiation Therapy (EBRT); absorbed dose heterogeneity is thought to be one important reason, together with a low absorbed dose rate, but the knowledge of microsphere distributions is limited. READ MORE