Search for dissertations about: "normal tissues"

Showing result 1 - 5 of 490 swedish dissertations containing the words normal tissues.

  2. 1. Human secretoglobins in normal and neoplastic cells and tissues

    Author : Anna Sjödin; Håkan Hedman; Roger Henriksson; Mårten Fernö; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; secretoglobins; mammaglobin; lipophilin; breast cancer; pituitary; sweat gland; Onkologi; Oncology; Onkologi; onkologi; Oncology;

    Abstract : Secretoglobins is a newly described polypeptide family that has gained a lot of interest in human cancer and inflammation research. Although the first secretoglobin polypeptide was discovered more than 30 years ago, their physiological function is still not known. READ MORE

  4. 2. ARCON in experimental and clinical radiotherapy

    Author : Ana Maria Rojas Callejas; Björn Zackrisson; René-Olivier Mirimanoff; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; ARCON; tumours; normal tissues; radiosensitization; carbogen; nicotinamide; repair inhibition; therapeutic gain; rodents; humans; Onkologi; Oncology; Onkologi; onkologi; Oncology;

    Abstract : xHypoxia and repopulation of tumour clonogens are two important determinants of treatment outcome in radiotherapy. In general clinical evidence indicates that loco-regional control may be reduced with long overall treatment times and for tumours with low pre-treatment levels of oxygen. READ MORE

  5. 3. Bestrophin-3: Localization and function in normal and injured tissues

    Author : Veronika Golubinskaya; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bestrophin-3; alternative splicing; injury;

    Abstract : Bestrophin-3 (Best3) is a protein with multiple functions. It can constitute a calcium-activated chloride channel when overexpressed in cultured cells, but the function of Best3 is not well studied in cells in situ. Recently Best3 protein was suggested to play also cell-protective role. READ MORE

  6. 4. Radiolabeled acetate PET in oncology imaging : studies on head and neck cancer, prostate cancer and normal distribution

    Author : Aijun Sun; Jens Sörensen; Silvia Johansson; Mikael Karlsson; Katrine Åhlström Riklund; Ingela Turesson; Heikki Minn; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 11C-acetate; 18F-fluoroacetate; PET; head and neck cancer; staging; delineating tumor volume; clearance rate; perfusion; RT; treatment outcome; benign and malignant lymph node; prostate cancer; normal distribution; Oncology; Onkologi; onkologi; Oncology;

    Abstract : The use of positron emission tomography (PET) for imaging in oncology has grown rapidly in recent years. 2-[18F]-fluorodeoxyglucose (FDG) is the most common tracer of PET, although drawbacks exist. READ MORE

  7. 5. DNA Damage Response of Normal Epidermis in the Clinical Setting of Fractionated Radiotherapy : Evidence of a preserved low-dose hypersensitivity response

    Author : Fredrik Qvarnström; Ingela Turesson; Gunilla Enblad; Mats Harms-Ringdahl; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; DNA damage response; low-dose hypersensitivity; dose response; normal tissue; epidermis; keratinocyte; fractionated radiotherapy; DNA double strand break; DSB; foci; γH2AX; 53BP1; checkpoint; p21; apoptosis; mitosis; Oncology; Onkologi; Oncology; onkologi;

    Abstract : Investigations of DNA damage response (DDR) mechanisms in normal tissues have implications for both cancer prevention and treatments. The accumulating knowledge about protein function and molecular markers makes it possible to directly trace and interpret cellular DDR in a tissue context. READ MORE