Search for dissertations about: "novel biomarkers"

Showing result 1 - 5 of 350 swedish dissertations containing the words novel biomarkers.

  2. 1. Proteomic Analysis of Urinary Bladder Cancer : Aiming for Novel Biomarkers

    Author : Mårten Lindén; Per-Uno Malmström; Ulrika Segersten; Sara Bergström Lind; Lars Egevad; Uppsala universitet; []
    Keywords : urine; APOE; FGB; GAL1; LRG1; POLR1E; SERPINA1; STMN1; TOP2A; biomarker; diagnostic biomarker; prognostic biomarker; predictive biomarker; mass spectrometry; western blot; dot blot; immunohistochemistry; IHC; tissue microarray; TMA; urothelium; antibody; antibody-based; urinblåsecancer; biomarkör; diagnos; prognos; urin; proteomik; masspektrometri; immunohistokemi; antikroppar; Molecular Biology; Molekylärbiologi; Molekylär medicin; Molecular Medicine;

    Abstract : Urinary bladder cancer is a heterogeneous disease appearing in different forms, e.g. non-muscle invasive and muscle invasive. For all variants, the expression of proteins is interesting to analyze for diagnostic, predictive, prognostic and drug targeting purposes, since it reflects the altered gene expression causing the cancer. READ MORE

  4. 2. ANALYSIS OF NOVEL BIOMARKERS FOR UNFAVORABLE BREAST CANCER PROGNOSIS

    Author : Emman Shubbar; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ductal Carcinoma In Situ DCIS ; Primary invasive breast cancer; Biomarkers;

    Abstract : Breast cancer is the most common malignancy in women, and a major cause of mortality and morbidity despite the advances in diagnosis and treatment. The main challenge remains to identify novel biomarkers in order to improve existing treatment modalities. Ductal carcinoma in situ (DCIS) is considered as a direct precursor of invasive breast cancer. READ MORE

  5. 3. Beyond the established risk factors of myocardial infarction : lifestyle factors and novel biomarkers

    Author : Patrik Wennberg; Jan-Håkan Jansson; Mai-Lis Hellénius; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; lifestyle factors; physical activity; commuting activity; leisure time physical activity; occupational physical activity; snuff use; haemostatic markers; inflammatory markers; myocardial infarction; epidemiology; primary prevention.; Family medicine; Allmänmedicin; Family Medicine; allmänmedicin;

    Abstract : Age, male sex, hypertension, smoking, diabetes, dyslipidaemia, and obesity are considered as established risk factors for cardiovascular diseases. Several of these established cardiovascular risk factors are strongly influenced by lifestyle. READ MORE

  6. 4. Novel Cutaneous Human Papillomaviruses and Biomarkers in the Skin Lesions

    Author : Natasa Vasiljevic; Malmö Klinisk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prevalence; E7 protein; Non-melanoma skin cancer; biomarkers; keratoachantoma; Human papillomavirus;

    Abstract : Non-melanoma skin cancer (NMSC), comprising of squamous cell carcinoma (SCC) and basal cell carcinoma (BCC), is the most prevalent cancer amongst Caucasians. The main risk factor for the development of NMSC is UV-irradiation but human papillo-mavirus (HPV) might be a co-factor. READ MORE

  7. 5. Small Intestinal Neuroendocrine Tumors : Clinical Studies, Novel Serum Biomarkers and Sensitivity to Cytotoxic and Targeted Agents

    Author : Kosmas Daskalakis; Peter Stålberg; Per Hellman; Olov Norlén; Robert Bränström; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SI-NET; fibrosis; locoregional surgery; liver transplantation; biomarkers; ex vivo sensitivity.;

    Abstract : Small Intestinal Neuroendocrine Tumors (SI-NETs) are indolent neoplasms with an increasing annual incidence of approximately 1/100 000 people. They are often diagnosed at a late stage, restricting treatment efficacy. READ MORE