Search for dissertations about: "novel drugs"

Showing result 1 - 5 of 562 swedish dissertations containing the words novel drugs.

  2. 1. Novel Psychoactive Substances : Experienced effects, attitudes, and motivations among online drug community users

    Author : Christophe Soussan; Anette Kjellgren; Anna Stigsdotter Neely; Torsten Passie; Karlstads universitet; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Novel psychoactive substances; drugs; legal highs; Internet; forum; ethylphenidate; discussions; motivations; harm reduction; substance displacement; Psykologi; Psychology;

    Abstract : The aim of the present research is to contribute to the bridging of the knowledge gap pertaining to the field of Novel Psychoactive Substances (NPS) and its online community of users. The findings demonstrate that the community is characterized by robust group cohesiveness and counter public attitudes. READ MORE

  4. 2. Molecular Profiling and Imaging of Peptides, Proteins and Drugs in Biological Tissue using Mass Spectrometry

    Author : Anna Nilsson; Per E. Andrén; Garry Corthals; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; peptidomics; mass spectrometry; liquid chromatography; MALDI imaging; neuropeptides; drugs; brain; Pharmacology; Farmakologi;

    Abstract : Biological functions within cells and organisms are mainly carried out by the translational products; proteins and peptides. The analysis and characterization of these biomolecules are of great importance for the progress in disease research and biomarker and drug discovery. READ MORE

  5. 3. The genetics of schizophrenia : sex, drugs, and cognition

    Author : Elise Koch; Karolina Kauppi; Lars Nyberg; Anders Lundquist; Alessandro Serretti; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; schizophrenia; genetics; cognition; sex differences; polygenic risk; fMRI; network medicine; drug repurposing; precision medicine;

    Abstract : Cognitive impairment constitutes an important predictor of general functional outcomes in schizophrenia. Polygenic risk for schizophrenia has been linked to cognitive ability as well as brain activation during cognitive processing. READ MORE

  6. 4. Pharmacokinetics of antidepressant drugs : naturalistic and clinical trials

    Author : Margareta Reis; Finn Bengtsson; Edoardo Spina; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Depression is a major public health problem and it is predicted to be the second leading cause of disease burden by the year 2020. The pharmacological treatment period for major depressive disorder (MDD) is relatively long and sometimes prophylactic over many years. READ MORE

  7. 5. Drug Repositioning for Cancer Treatment : Novel Candidate Identification Strategies

    Author : Madiha Nazir; Mårten Fryknäs; Sigurd Vitols; Uppsala universitet; []
    Keywords : cancer treatment; drug repositioning; Phosphodiesterase 3A PDE3A ; apoptosis; combination screening;

    Abstract : Regardless of the enormous investments in cancer research and drug development, the proportion of approved drugs in oncology is low compared to other indications, and new avenues are needed. One attractive approach in this regard is drug repositioning where new uses outside the scope of the original medical indications for existing drugs are identified. READ MORE