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Showing result 1 - 5 of 7 swedish dissertations matching the above criteria.

  2. 1. Fungal Lectins. Molecular structure and function of a member of a novel lectin family

    Author : Stefan Rosén; Biologiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; possible functions; expression; localization; binding specificities; primary and secondary structure; Agaricus bisporus; Arthrobotrys oligospora; Fungi; novel lectin family; Biology; Biologi;

    Abstract : Lectins defined as non-enzyme, non-immunoglobulin carbohydrate binding proteins, have been found in a wide variety of viruses, bacteria, fungi, plants and animals. Although lectins have been purified from more than 60 different species of fungi, the structure and biological functions of these proteins are not well known. READ MORE

  4. 2. Clinical and genetic studies of three inherited skeletal disorders

    Author : Eva-Lena Stattin; Göran Roos; Niklas Dahl; Jaakko Ignatius; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; skeletal disorders; osteochondritis dissecans; ACAN-gene; multiple epiphyseal dysplasia; brachydactyly type A1; IHH-gene; Medical genetics; Medicinsk genetik; klinisk genetik; Clinical Genetics;

    Abstract : Mutations in genes of importance for cartilage development may lead to skeletal malformations, chondroskeletal dysfunction and increased susceptibility to degenerative joint disease. Characterization of these mutations and identification of molecular pathways for the corresponding gene products have contributed to our understanding of mechanisms regulating skeletal patterning, endochondral ossification and joint formation. READ MORE

  5. 3. Complement in Disease - Extracellular Proteins as Complement Regulators

    Author : Kaisa Happonen; Malmö Proteinkemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rheumatoid arthritis; joint disease; Complement; proteoglycan; cancer;

    Abstract : Complement activation occurs during inflammatory joint diseases such as rheumatoid arthritis (RA) and is thought to contribute to the chronic inflammation observed within the joints. Previous studies have shown that certain cartilage components of the small leucine-rich repeat protein (SLRP)-family regulate complement activity, thereby possibly contributing to disease progression. READ MORE

  6. 4. Mucus associated proteins and their functional role in the distal intestine

    Author : Joakim H. Bergström; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; intestine; mucus; bacteria; MUC2; AGR2; FCGBP; ZG16;

    Abstract : The mammalian intestine, especially the large intestine, harbors complex societies of beneficial bacteria coexisting with the host. This is a mutualistic relationship, where the host provides nutrients and a favorable environment while the bacteria in return ferment indigestible polysaccharides to short chain fatty acids. READ MORE

  7. 5. Polymorphism in pattern recognition receptor genes in pigs

    Author : Ingrid-Maria Bergman; Inger Edfors; Kristina Nilsson Ekdahl; Kjell Edman; Dag Inge Våge; Linnéuniversitetet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Genetics; Genetik; Biomedical Sciences; Biomedicinsk vetenskap;

    Abstract : The mammalian immune defense consists of two systems, which are interconnected and co-operate to provide host defense. The innate immune system is always active and detects and responds to non-self without delay. The adaptive immune system has a lag phase, but is more specific and has got a memory. READ MORE