Search for dissertations about: "novel treatment for malaria"

Showing result 1 - 5 of 13 swedish dissertations containing the words novel treatment for malaria.

  2. 1. Novel treatment strategies for multidrug-resistant tuberculosis

    Author : Lina Davies Forsman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Tuberculosis is the leading cause of death from a single infectious agent in the world, surpassing the annual death toll of both malaria and HIV combined. The rise in multidrug-resistant tuberculosis (MDR-TB) has further exacerbated the situation, as this form of TB is more difficult and time-consuming to treat, with dismal cure rates. READ MORE

  4. 2. Malaria and relapsing fever Borrelia : interactions and potential therapy

    Author : Jenny Lundqvist; Cathrine Persson; Antonio Barragan; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Malaria; Plasmodium; relapsing fever; Borrelia; persistent; concomitant infections; polyamines; Molecular biology; Molekylärbiologi; Microbiology; immunology; infectious diseases; Mikrobiologi; immunologi; infektionssjukdomar; molekylär bioteknik inst f molekylärbiologi ; molecular biotechnology dept of molecular biology ; Infectious Diseases; infektionssjukdomar;

    Abstract : Infectious diseases such as malaria and relapsing fever borreliosis (RF), cause severe human mortality and morbidity in developing countries. Malaria, caused by Plasmodium spp. parasites, is estimated by the World Health Organization to cause 1.5-2. READ MORE

  5. 3. Structure-Assisted Design of Drugs Towards HIV-1 and Malaria Targets : Applied on Reverse Transcriptase and Protease from HIV-1 and Plasmepsin II from Plasmodium falciparum

    Author : Jimmy Lindberg; Torsten Unge; Alexander Wlodawer; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; X-ray crystallography; Drug design; HIV-1; Malaria; Molekylärbiologi; Molecular biology; Molekylärbiologi;

    Abstract : Globally of today, acquired immunodeficiency syndrome (AIDS) and malaria are two of the most threatening diseases known to mankind. The World Health Organization estimated that AIDS and malaria together claimed nearly 4 million lives in 2003 and many more were infected by the causative agent human immunodeficiency virus (HIV) and the Plasmodium falciparum (P. READ MORE

  6. 4. Development of Analytical Methods for the Determination of Antimalarials in Biological Fluids

    Author : Daniel Blessborn; Yngve Bergqvist; Anders Helander; Högskolan Dalarna; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Malaria; Chloroquine; Quinine; Sulfadoxine; Pyrimethamine; Mefloquine; Lumefantrine; Amodiaquine; Pyronaridine; Proguanil; Atovaquone; Sampling paper; Dried blood spots; Capillary blood; Antimalarial drugs; Solid-phase extraction; Liquid chromatography.; Chemistry;

    Abstract : The aim of this thesis was to develop analytical methods for measuring antimalarial drugs in biological fluids. Solid phase extraction (SPE) was used for the enrichment and purification of the drugs. READ MORE

  7. 5. Novel combination chemotherapy for treatment and control of schistosomiasis among school children

    Author : Rajabu Hussein Mnkugwe; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Despite reported success in reducing severe disease-associated morbidities in endemic countries, praziquantel (PZQ) alone has failed to control and eliminate schistosomiasis, partly due to its poor efficacy against immature/juvenile worms. Artemisinin derivatives are efficacious against juvenile schistosomes. READ MORE