Search for dissertations about: "npl"
Showing result 1 - 5 of 11 swedish dissertations containing the word npl.
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1. Genetic susceptibility to psoriasis in Sweden
Abstract : A common skin disease affecting about 2-3% of the population, psoriasis has an inheritance pattern that is unclear, but most probably many genes are involved in its pathogenesis. Other studies have suggested many susceptibility regions in the genome, but as yet independent studies have replicated only some of these regions located on chromosome 1q, 6p and 17q. READ MORE
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2. Pointwise and Genomewide Significance Calculations in Gene Mapping through Nonparametric Linkage Analysis: Theory, Algorithms and Applications
Abstract : In linkage analysis or, in a wider sense, gene mapping one searches for disease loci along a genome. This is done by observing so called marker genotypes (alleles) and phenotypes (affecteds/unaffecteds) of a pedigree set, i.e. READ MORE
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3. On Power Estimation and Score Predictions in Affected Sib-Pair Linkage Analysis
Abstract : This thesis consists of three papers in statistical genetics, with the emphasis on affected sib-pair linkage analysis. In Paper A, a method to derive the power of linkage analysis in genome scans, using a stepwise approach, is presented. READ MORE
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4. Natural Ventilation and Air Infiltration in Large Single‑Zone Buildings : Measurements and Modelling with Reference to Historical Churches
Abstract : Natural ventilation is the dominating ventilation process in ancient buildings like churches, and also in most domestic buildings in Sweden and in the rest of the world. These buildings are naturally ventilated via air infiltration and airing. READ MORE
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5. Genetic and epidemiological studies of dystocia : difficult labour
Abstract : Objective: To explore the epidemiological characteristics, the influence on reproductive health and the genetic basis of dystocia prolonged and difficult labour. Material and methods: The thesis has a retrospective design and is mainly based on a material from an entire cohort of women, extracted from the Swedish Medical Birth Register, who had their first delivery during the years 1973 to 1997. READ MORE