Search for dissertations about: "nuclear-mitochondrial interaction"
Found 2 swedish dissertations containing the words nuclear-mitochondrial interaction.
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1. Mitochondrial and chromosomal genomics in type 2 diabetes
Abstract : Understanding the mechanisms of complex polygenic diseases like type 2 diabetes (T2D) is as complex as their nature. Cellular processes involved in glucose homeostasis need high and reliable energy supply. Mitochondria are the major energy producers in mammalian cells. READ MORE
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2. DNA damage-induced cell death : the role of caspase-2
Abstract : Activation of a family of cysteine proteases, called caspases, is an important event during apoptosis. In comparison to other caspases, less is known about regulatory functions of caspase-2. Previous studies from our group established caspase-2 as an essential apical regulator of apoptosis triggered by DNA damage. READ MORE