Search for dissertations about: "nucleophilic substitution reactions"
Showing result 16 - 19 of 19 swedish dissertations containing the words nucleophilic substitution reactions.
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16. Development of novel fluorine-18 labeled PET radioligands for monoamine oxidase B (MAO-B)
Abstract : Monoamine oxidases (MAO-A and MAO-B) are important enzymes regulating the levels of monoaminergic neurotransmitters. Selective and irreversible MAO-B inhibitors such as L-deprenyl and rasagiline are clinically used for the treatment of psychiatric and neurological disorders. READ MORE
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17. Molecular mechanisms and complete antigen formation in allergic contact dermatitis
Abstract : Allergic contact dermatitis (ACD) is a common T cell mediated skin disease. Small reactive organic molecules called haptens induce ACD. Haptens are not recognized by themselves, but need to bond to endogenous proteins in the skin, and processed further into complete antigens. Antigen specific T cells then recognize the resulting antigen. READ MORE
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18. Chemical and Dermatological Aspects of UV-absorbing Compounds
Abstract : ABSTRACT The sun’s UV radiation is necessary for the existence of life on earth. However, too much UV exposure can lead to the development of skin cancer. Therefore, sunscreens are often used by the general population as protection from excessive UV radiation. READ MORE
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19. New Reactivity in Diaryliodonium Salt Chemistry
Abstract : Diaryliodonium salts (Ar2IX) have emerged as versatile multi-purpose reagents with desirable properties such as easy accessibility, low toxicity and applicability under mild and metal-free reaction conditions. Despite displaying broad utility in arylations of both carbon and heteroatom nucleophiles, the overall sustainability of these protocols is compromised by featuring poor atom economy due to the formation of stochiometric iodoarene byproducts. READ MORE