Search for dissertations about: "nucleophilic substitution"

Showing result 1 - 5 of 33 swedish dissertations containing the words nucleophilic substitution.

  2. 1. Palladium-Catalyzed Nucleophilic Substitution of Alcohols : Mechanistic Studies and Synthetic Applications

    Author : Supaporn Sawadjoon; Joseph Samec; Takao Ikariya; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; palladium; nucleophilic substitution; mechanism; Organic Chemistry; Organisk kemi;

    Abstract : This thesis deals with the palladium-catalyzed nucleophilic substitution of π-activated alcohols in which the C–O bond of a non-manipulated hydroxyl group is cleaved. The thesis is divided in two chapters describing two different catalytic systems. READ MORE

  4. 2. Direct Catalytic Nucleophilic Substitution of Non-Derivatized Alcohols

    Author : Anon Bunrit; Joseph Samec; Joseph Moran; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; nucleophilic substitution; catalysis; alcohols; stereospecific; Lewis acid; Brønsted acid base; bifunctional; heterocycles; organisk kemi; Organic Chemistry;

    Abstract : This thesis focuses on the development of methods for the activation of the hydroxyl group in non-derivatized alcohols in substitution reactions. The thesis is divided into two parts, describing three different catalytic systems. READ MORE

  5. 3. Copper-Mediated Vicarious Nucleophilic Substitution

    Author : Olof Haglund; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : This thesis suggests and examines a novel approach for copper-mediated cross-couplings. We call this mechanistic approach copper-mediated vicarious nucleophilic substitution. Our hypothesis is that copper-promoted cross-couplings proceed via an intermediate s-adduct, a Meisenheimer adduct. READ MORE

  6. 4. Copper-Mediated Vicarious Nucleophilic Substitution

    Author : Olof Haglund; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : .... READ MORE

  7. 5. Concerted or Stepwise? : β-Elimination, Nucleophilic Substitution, Copper Catalysed Aziridination and Ruthenium Catalysed Transfer Hydrogenation Studied by Kinetic Isotope Effects and Linear Free-Energy Relationships

    Author : Per Ryberg; Heinz F. Koch; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Kinetic isotope effect; linear free energy relationship; elimination; substitution; aziridination; transfer hydrogenation; Organisk kemi; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

    Abstract : This thesis describes the use of kinetic isotope effects, linear free energy relationships and stereochamical studies to distinguish between different mechanistic alternatives and to obtain information about transition state structure.In the first part fluorine and deuterium kinetic isotope effects were determined for the base promoted HF elimination from 4-fluoro-4-(4’-nitrophenyl)butane-2-on. READ MORE