Search for dissertations about: "o-linked glycans"

Showing result 11 - 13 of 13 swedish dissertations containing the words o-linked glycans.

  1. 11. Development and Evaluation of Tools to Explore Posttranslational HexNAc-Tyrosine and Mucin-Type O-Glycosylation

    Author : Sandra Behren; Ulrika Westerlind; Mikael Elofsson; Carmen Galan; Umeå universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Glycopeptides; mucins; mucin type-O-glycosylation; microarrays; tyrosine-O-HexNAcylation; lectins; MUC1 cancer vaccines; TcdA; LecB; galectins; LacdiNAc; antibodies; biologisk kemi; biological chemistry; Biorganic Chemistry; bioorganisk kemi; organisk kemi; Organic Chemistry;

    Abstract : Glycosylation is the most abundant form of post-translational modification (PTM). Recently, O-glycosylation attracted much attention in the glycoproteomic field due to its association with various diseases, such as pathogenic infections and cancer. READ MORE

  2. 12. Studies on O-glycosylation of mucin-type proteins and their binding to antibodies, bacterial toxins and viral receptors

    Author : Stefan Gaunitz; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Carbohydrates are ubiquitous on the surface of all cells in mammals where they are involved in interactions with the surroundings (extracellular matrix), other cells (including self and non-self) and microbes (bacteria and virus). Carbohydrate-protein interactions in nature are often mediated via multivalent binding where the combined strength of multiple receptor- ligand interactions results in a binding that is highly specific and strong. READ MORE

  3. 13. Free oligosaccharides and glycosylation of bile salt-stimulated lipase in human milk

    Author : Eva Landberg; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Bile salt-stimulated lipase (BSSL) is a glycosylated protein present in milk at a concentration of 100-200 mg/L. It is an enzyme important for fat digestion in the newborn infant. The protein backbone contains one possible site for N-glyeosylation and several sites for 0-glyeosylation. READ MORE