Search for dissertations about: "o-linked glycans"

Showing result 6 - 10 of 13 swedish dissertations containing the words o-linked glycans.

  1. 6. Immune recognition and early virus-cell interactions. Glycobiological aspects on HIV-1 gp120

    Author : Gregers J. Gram; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Human immunodeficiency virus type 1 HIV-1 ; glycoprotein; gp120; glycosylation.;

    Abstract : Human immunodeficiency virus types 1 and 2 (HIV-1 and HIV-2) are the etiological agents of AIDS in humans. The viral envelope glycoproteins gp120 and gp41 mediate the early virus-cell interaction of HIV with the target cells. READ MORE

  2. 7. Targeting the human glycoproteome: new enrichment protocols and mass spectrometric analyses reveal unique and novel glycosylation sites

    Author : Adnan Halim; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : Glycobiology; Glycoproteomics; Mass Spectrometry;

    Abstract : Glycosylation is one of the most common and structurally diverse posttranslational modifications of proteins. Given that protein glycosylation is involved in various cellular processes, the characterization of site-specific N- and O-linked glycosylations is becoming increasingly important. However, current mass spectrometry-based technologies, i.e. READ MORE

  3. 8. The role of polysaccharide modifications during Drosophila development

    Author : Florian Lüders; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ontogeni; growth animal ; embryologi; Development biology; Decapentaplegic; Hedgehog; Wingless; Sulfation; Pipe; Glycosaminoglycan; Glycosyltransferase; ontogeny; embryology; Utvecklingsbiologi;

    Abstract : Glucosides attached to proteins and lipids have been shown to modulate the activity of signal transduction pathways regulating growth and patterning processes during animal development. In particular, O-linked glycans such as glycosaminoglycans (GAGs) have been implicated in modulation of growth factor signaling pathways. READ MORE

  4. 9. Pichia pastoris as a platform for the production of therapeutic glycoproteins

    Author : Magnus Sjöblom; Luleå tekniska universitet; []

    Abstract : Recombinant protein therapeutics is a growing market within the human medical biotechnology industry. The majority of all approved biopharmaceuticals are protein based and includes for example blood factors, anticoagulants, hormones, vaccine and monoclonal antibodies. READ MORE

  5. 10. Recombinant mucin-immunoglobulin chimeras as xenoreactive anti-pig antibody absorbers

    Author : Jining Liu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Human allotransplantation is nowadays the generally accepted treatment of choice for several illnesses leading to organ failure. A major problem facing clinical organ transplantation is the lack of human donor organs and tissues. Xenotransplantation from pig to man is considered a plausible solution to this problem. READ MORE