Search for dissertations about: "obesity genetic"

Showing result 1 - 5 of 158 swedish dissertations containing the words obesity genetic.

  2. 1. Obesity Genetics : Functional Aspects of Four Genetic Loci Associated with Obesity and Body Mass

    Author : Mathias Rask-Andersen; Helgi Schiöth; Ingrid Dahlman; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Obesity is a complex disorder which has reached epidemic proportions in many parts of the world. Twin studies have demonstrated a high heritability for obesity. The subsequent appli-cation of genome wide association studies (GWAS) in the last decade have identified at least 32 genetic loci associated with body mass and obesity. READ MORE

  4. 2. Obesity and Increased Susceptibility : Role of FTO and MGAT1 Genetic Variants

    Author : Josefin A Jacobsson; Robert Fredriksson; Helgi B Schiöth; Sadaf Farooqi; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obesity; BMI; SNP; haplotype; association study; FTO; MGAT1; Pharmacology; Farmakologi; Farmakologi; Pharmacology;

    Abstract : Obesity is a complex and a highly individualized disease and the molecular mechanisms behind this disorder need to be better elucidated. Identification of genes and genetic variants that are involved provide opportunities to establish a genetic understanding of the disease. READ MORE

  5. 3. Pathogenesis of Obesity and Effects of Treatment. Clinical and Molecular Studies on Body Fat, Energy Balance, and Weight Loss

    Author : Anders Gummesson; Göteborgs universitet; []
    Keywords : Obesity; Adipose tissue; Obesity treatment; Energy balance; Visceral obesity; Weight loss; Cancer; Human studies;

    Abstract : Obesity is common and related to many health problems including various forms of cancer. The condition arises from the imbalance between food intake and energy expenditure, and is strongly influenced by genetic factors. READ MORE

  6. 4. Environmental Contaminants and Obesity

    Author : Monika Rönn; P. Monica Lind; Lars Lind; Jan Örberg; Merete Eggesbø; Uppsala universitet; []
    Keywords : Fischer 344; rat; obesity; adipose tissue; persistent organic pollutants; POPs; bisphenol A; BPA; pesticides; dioxin; PCB; DDT; apo A-I; adiponectin; leptin; ghrelin;

    Abstract : Obesity is a worldwide problem affecting both children and adults. Genetic, physiological, environmental, psychological, social and economic factors interact in varying degrees, influencing body weight and fat distribution and the progress of obesity. READ MORE

  7. 5. The human pancreatic polypeptide receptor Y4 : Genetic and functional variation

    Author : Kateryna Shebanits; Dan Larhammar; Sadaf Farooqi; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NPY4R; Y4; obesity; CNV; Medicinsk vetenskap; Medical Science;

    Abstract : Humans are evolutionarily adapted to an environment where food is scarce, but today many live in a world of food abundance. Paired with low physical activity, this may lead to weight gain and obesity. Efficient anti-obesity treatments require understanding of the mechanisms that control hunger, satiety, energy metabolism and body weight. READ MORE