Search for dissertations about: "obesity leptin"

Showing result 1 - 5 of 76 swedish dissertations containing the words obesity leptin.

  2. 1. Leptin : a risk marker for cardiovascular disease

    Author : Stefan Söderberg; Ulf de Faire; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; leptin; testosterone; dysfibrinolysis; hyperinsulinemia; insulin resistance syndrome; menopause; cardiovascular disease; MONICA; epidemiology;

    Abstract : A major cause of morbidity and early death in the Western societies is cardiovascular disease (CVD) secondary to atherosclerotic disease. Metabolic aberrations have been linked to CVD. READ MORE

  4. 2. Genes implicated in the development of obesity and obesity-related disease

    Author : Kajsa Lindell; Göteborgs universitet; []
    Keywords : obesity; adipose tissue; hypothalamus; leptin; leptin receptor; 5 untranslated region; hypertension; angiotensinogen; DNA microarray;

    Abstract : Obesity is a major health problem because of its dramatic increase in prevalence and the association of obesity with type 2 diabetes, coronary heart disease, hypertension and stroke. Although mutations in certain genes have been shown to cause obesity, the molecular mechanisms underlying obesity and obesity-related disease are still largely unknown. READ MORE

  5. 3. Environmental Contaminants and Obesity

    Author : Monika Rönn; P. Monica Lind; Lars Lind; Jan Örberg; Merete Eggesbø; Uppsala universitet; []
    Keywords : Fischer 344; rat; obesity; adipose tissue; persistent organic pollutants; POPs; bisphenol A; BPA; pesticides; dioxin; PCB; DDT; apo A-I; adiponectin; leptin; ghrelin;

    Abstract : Obesity is a worldwide problem affecting both children and adults. Genetic, physiological, environmental, psychological, social and economic factors interact in varying degrees, influencing body weight and fat distribution and the progress of obesity. READ MORE

  6. 4. Trends in obesity and type 2 diabetes : ethnic aspects and links to adipokines

    Author : Mikael Lilja; Stefan Söderberg; Olov Rolandsson; Mats Eliasson; Kurt Svärdsudd; Umeå universitet; []
    Keywords : Type 2 diabetes; leptin; adiponectin; obesity; abdominal obesity; epidemiology; ethnicity; fasting glucose; post-load glucose; Family Medicine; allmänmedicin;

    Abstract : Objective The prevalence of obesity and related diseases such as type 2 diabetes mellitus (T2DM) is increasing worldwide, and the Asian Indian population seems to be particularly susceptible to developing T2DM, even at a low body mass index (BMI). In Sweden, the age-adjusted prevalence of diabetes has not increased despite increasing self-reported obesity. READ MORE

  7. 5. The role of leptin in endothelial dysfunction and cardiovascular disease

    Author : Manuel Cruz Gonzalez Garcia; Stefan Söderberg; Jan Engvall; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; leptin; obesity; endothelial dysfunction; cardiovascular disease; kardiologi; Cardiology;

    Abstract : Objective:  Obesity has become the leading cause of mortality worldwide; however, the fundamental pathophysiology underlying this association remains unclear. The discovery of adipokines, i.e., cytokines produced by adipose cells (adipocytes), revealed that adipose tissue is a highly endocrine organ, thus opening new lines of investigation. READ MORE