Search for dissertations about: "olfactory bulb interneurons"

Showing result 1 - 5 of 7 swedish dissertations containing the words olfactory bulb interneurons.

  2. 1. The Role of miRNA in Neurogenesis and Cell Specification

    Author : Malin Åkerblom; Molekylär neurogenetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; miRNA; microRNA; miR-124; miR-9; miR-125; adult neurogenesis; neural stem cells; cell specification; microglia; lentiviral vectors; olfactory bulb; olfactory bulb interneurons;

    Abstract : Only a few decades ago, it was generally believed that gene expression was controlled in a unidirectional way, i.e. DNA was transcribed into RNA, which simply acted as a messenger molecule used to produce the protein that executed cellular functions. READ MORE

  4. 2. The Regulatory Role of microRNAs in the Mouse and Human Brain

    Author : Rebecca Petri; Molekylär neurogenetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; microRNA; Argonaute; AGO-RIP; let-7; miR-125; adult neurogenesis; olfactory bulb; autophagy; transposable elements; LINE-2; Huntington’s disease;

    Abstract : microRNAs (miRNAs) are 20-24 nucleotides small, single-stranded, non-coding RNAs. They associate with Argonaute (AGO) proteins and exert their function by inhibition or degradation of messenger RNAs. READ MORE

  5. 3. Brain-derived neurotrophic factor and endocannabinoid functions in gabaergic interneuron development

    Author : Paul Berghuis; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Formation of the cerebral cortex is controlled by tightly regulated processes: the proliferation and survival decisions of neural progenitors, radial and tangential migration of neuronal precursors, axon guidance and dendritic growth underpinning the formation of synapses. Patterning of the neocortex has been extensively studied and significant progress has been made in understanding the principles of cortical neuronal circuit formation. READ MORE

  6. 4. Progenitor cells in the postnatal central nervous system, characterization and genetic manipulation

    Author : Nina Rogelius; CNS Genterapi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Medicine human and vertebrates ; subventricular zone; Islet1; Neurogenin2; respecification; in vivo.; transcription factors; neurogenesis; Progenitor cells; stem cells;

    Abstract : New neurons are only generated in two places of the postnatal brain; the subventricular zone (SVZ) and hippocampus. The SVZ-derived cells specifically migrate to the olfactory bulb where they give rise to new interneurons. READ MORE

  7. 5. Stem cells in inflammation and regeneration : focusing on animal models of multiple sclerosis and spinal cord injury

    Author : Sreenivasa Raghavan Sankavaram; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The main objective of regenerative medicine is to replace or restore injured cells and tissues in the body. Stem cells are identified playing a key role in the regeneration but action of inflammatory mediators in disease is not well understood. READ MORE