Search for dissertations about: "oligomerization"

Showing result 1 - 5 of 67 swedish dissertations containing the word oligomerization.

  1. 1. Oligomerization of human and bacterial frataxin : Structural and functional studies

    University dissertation from Lund University, Faculty of Science, Department of Chemistry, Division of Biochemistry and Structural Biology

    Author : Mostafa Abdalkhalik; [2017-02]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Frataxin; Friedreich’s ataxia; iron; reactive oxiden species; protein oligomerization; SAXS; EM; cross-linking; XAFS; nano- DSF;

    Abstract : Friedreich’s ataxia (FRDA) is an autosomal recessive neurodegenerative disease caused by defeciency in frataxin, a highly conserved protein central to iron homeostasis in mirochondria. The function of frataxin is related to its capability to bind, store and deliver iron to different biochemical process such as iron-sulfur cluster assembly and heme biosynthesis. READ MORE

  2. 2. Plant UDP-glucose Pyrophosphorylase Function and Regulation

    University dissertation from Umeå : Fysiologisk botanik

    Author : Meng Meng; Leszek Kleczkowski; Javier Pozueta-Romero; [2008]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; UDP-glucose pyrophosphorylase; carbohydrate metabolism; in vivo regulation; T-DNA knockout; heterologous expression; isozyme; mutagenesis; kinetic property; oligomerization; NATURAL SCIENCES Biology Organism biology Plant physiology; NATURVETENSKAP Biologi Organismbiologi Växtfysiologi;

    Abstract : UDP-glucose pyrophosphorylase (UGPase) is an important enzyme of carbohydrate metabolism in all living organisms. The main aim of this thesis was to investigate the function and regulation of plant UGP genes as well as the UGPase proteins. READ MORE

  3. 3. UDP-sugar metabolizing pyrophosphorylases in plants formation of precursors for essential glycosylation-reactions

    University dissertation from Umeå : Umeå Universitet

    Author : Daniel Decker; Leszek A. Kleczkowski; Henrik Vibe Schelle; [2017]
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Chemical library screening; Cell wall synthesis; Glycosylation; Nucleotide sugars; Oligomerization; Protein structure; Reverse chemical genetics; Sugar activation; UDP-sugar synthesis; biokemisk farmakologi; biochemical pharmacology; biokemi; Biochemistry; biology; biologi; molekylärbiologi; Molecular Biology;

    Abstract : UDP-sugar metabolizing pyrophosphorylases provide the primary mechanism for de novo synthesis of UDP-sugars, which can then be used for myriads of glycosyltranferase reactions, producing cell wall carbohydrates, sucrose, glycoproteins and glycolipids, as well as many other glycosylated compounds. The pyrophosphorylases can be divided into three families: UDP-Glc pyrophosphorylase (UGPase), UDP-sugar pyrophosphorylase (USPase) and UDP-N-acety lglucosamine pyrophosphorylase (UAGPase), which can be discriminated both by differences in accepted substrate range and amino acid sequences. READ MORE

  4. 4. Multifaceted adaptation in adherence by the gastric pathogen Helicobacter pylori

    University dissertation from Umeå : Umeå Universitet

    Author : Yevgen Chernov; [2017]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; H. pylori; BabA; oligomerization; Leb; recombination; mutation; adherence; pH-sensitive; pH-resistant;

    Abstract : .... READ MORE

  5. 5. Leukotriene C4 synthase : studies on oligomerization and subcellular localization

    University dissertation from Linköping : Linköpings universitet

    Author : Jesper Svartz; Mats Söderström; Sven Hammarström; Colin Funk; [2005]

    Abstract : Leukotrienes (LTs) are polyunsaturated fatty acid derivatives formed by oxygenation of arachidonic acid via the 5-lipoxygenase (5-LO) pathway. Upon activation of inflammatory cells 5-LO is translocated to the nuclear envelope where it converts arachidonic acid to the unstable epoxide LTA4. READ MORE