Search for dissertations about: "oligosaccharide complex"
Showing result 1 - 5 of 13 swedish dissertations containing the words oligosaccharide complex.
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1. Intestinal mucins 'soluble and insoluble problems'
Abstract : Highly glycosylated glycoproteins – mucins – are the major constituents of the mucus layer and glycocalyx that cover mucosal surfaces. Twelve human mucin genes have been identified, and the mucins may be divided into those that are membraneassociated and those that are secreted. READ MORE
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2. Role of Heparan Sulfate Structure in FGF-Receptor Interactions and Signaling
Abstract : Heparan sulfate (HS) belongs to the glycosaminoglycan family of polysaccharides and is found attached to protein cores on cell surfaces and in the extracellular matrix. The HS backbone consists of alternating hexuronic acid and glucosamine units and undergoes a number of modification reactions creating HS chains with alternating highly and low modified domains, where high degree of modification correlates with high negative charge. READ MORE
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3. O-glycosylation of intestinal and respiratory mucins in health and disease
Abstract : Mucins are large glycoproteins with a diverse O-glycosylation constituting up to 80% of the total mucin mass. The mucus layer covering the epithelial cells of the gastrointestinal and respiratory tract is largely made up of gel-forming mucins. READ MORE
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4. Shedding light on glycosylation : Analysis of complex carbohydrates using an affinity biosensor
Abstract : The main objective during the work described in this thesis has been to develop assays for stodies of complex carbohydrates in a clinical context. Complex carbohydrates, such as free or protein linked oligosaccharides, have been shown to have important biological functions. READ MORE
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5. Structural diversity of the lipid A and core oligosaccharide moieties of the lipopolysaccharides from nontypeable and serotype f Haemophilus influenzae
Abstract : This thesis describes structural studies of the oligosaccharide and lipid A moieties of lipopolysaccharides (LPSs) isolated from disease-causing Haemophilus influenzae strains. The nontypeable strains were clinical isolates from the middle ear of children suffering from otitis media and the serotype f strains had been collected from three adults with respiratory tract infections. READ MORE