Search for dissertations about: "on anti arthritis activity"

Showing result 6 - 10 of 85 swedish dissertations containing the words on anti arthritis activity.

  2. 6. Health economics and its measures in rheumatoid arthritis

    Author : Johan Karlsson; Reumatologi och molekylär skelettbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cost-utility analysis; Cost-of-illness; Quality of life; EuroQol 5-Dimensions; Antirheumatic agents; TNF inhibition; Outcome assessment; Disease activity; Disability; Health economics; Rheumatoid arthritis;

    Abstract : Objectives: To study: (I) the impact on cost-utility analyses of applying different national EuroQol 5-Dimensions (EQ-5D) preference sets; (II and III) whether, in methotrexate-refractory, early rheumatoid arthritis (RA), the addition of infliximab results in superior health-related quality of life (HRQoL) and may be considered cost-effective, as compared to adding sulfasalazine and hydroxychloroquine; (IV) how costs relate to disability (measured by the health-assessment questionnaire, HAQ), disease activity (28-joint disease activity score, DAS28) and HRQoL (EQ-5D) in RA. Methods: In the observational SSATG register, one-year quality-adjusted life-year (QALY) accumulation of two interventions was compared according to the UK, US, or Danish EQ-5D preference sets. READ MORE

  4. 7. Disease activity, function and costs in early rheumatoid arthritis

    Author : Eva Hallert; Thomas Skogh; Jan Persson; Ronald van Vollenhoven; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Antirheumatic agents; Rheumatoid arthritis; Cost of illness; Health care costs; Joints physiopathology; Sex factors; Rheumatology; Reumatologi;

    Abstract : Rheumatoid arthritis (RA) is a major cause of progressive joint damage and disability, and is associated with decline in quality of life, reduced ability to work and increased health care utilisation. The economic consequences of the disease are substantial for the individuals and their families and for the society as a whole. READ MORE

  5. 8. Diet as a complementary therapy in Rheumatoid Arthritis - On the menu: An anti-inflammatory portfolio diet

    Author : Anna Turesson Wadell; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dietary intervention; diet; nutrition; rheumatoid arthritis;

    Abstract : Over the last two decades, pharmacological treatment in rheumatoid arthritis (RA) has evolved remarkably and is essential to suppress disease progress. Still, it often fails to provide satisfactory symptom relief suggesting a need for complementary treatment. READ MORE

  6. 9. Studies on novel immunosuppressive agents in experimental arthritis

    Author : Thi Ngoc Dzung Dang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Artocarpus Tonkinensis; Collagen-induced arthritis; apoptosis; immunosuppression;

    Abstract : Rheumatoid Arthritis (RA) is a chronic inflammatory disease of the joints. The hallmark of RA is persisting inflammation in diarthrodial joints with infiltration of leukocytes, thickening of the synovial lining layer and synovial pannus formation. READ MORE

  7. 10. The role of S100A4 protein as a regulator of inflammation and bone metabolism in experimental arthritis

    Author : Li Bian; Göteborgs universitet; []
    Keywords : S100A4; arthritis; animal model; bone; inflammation;

    Abstract : S100A4 belongs to the family of calcium-binding S100 proteins and modulates cell proliferation, cytoskeletal rearrangement, cell motility, and angiogenesis. Increased levels of S100A4 expression correlate with high incidence of metastasis of cancers. READ MORE