Search for dissertations about: "online liquid chromatography"

Showing result 1 - 5 of 17 swedish dissertations containing the words online liquid chromatography.

  2. 1. Analytical method development in liquid chromatography- mass spectrometry based metabolomics

    Author : Ida Erngren; Mikael Hedeland; Curt Pettersson; Torbjörn Arvidsson; Gérard Hopfgartner; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Analytical pharmaceutical chemistry; metabolomics; liquid chromatography; mass spectrometry; hydrophilic interaction liquid chromatography; Analytical Pharmaceutical Chemistry; Analytisk farmaceutisk kemi;

    Abstract : Metabolomics is the analytical field which aims at analyzing all small molecules, metabolites, in a biological system simultaneously. Currently no analytical methods are able to capture the entire metabolome, therefore, the analytical methods are often developed to be as general as possible. READ MORE

  4. 2. Characterisation of natural dissolved organic matter with liquid chromatography and high resolution mass spectrometry

    Author : Claudia Patriarca; Jonas Bergquist; Lars Tranvik; Per J.R. Sjöberg; Jeffrey A. Hawkes; Norbert Hertkorn; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; aquatic carbon cycle; dissolved organic matter; DOM; high resolution mass spectrometry; online liquid chromatography; organic matter characterization; Kemi med inriktning mot analytisk kemi; Chemistry with specialization in Analytical Chemistry;

    Abstract : Dissolved organic matter (DOM) is one of the most heterogeneous and complex mixture on Earth. DOM plays a crucial role in biogeochemical processes on the global scale and it is essential to sustain and regulate the biological processes in aquatic ecosystems. READ MORE

  5. 3. Automation, hyphenation and multidimensional chromatography for PAH analysis : Analytical techniques to simplify sample complexity

    Author : Hwanmi Lim; Roger Westerholm; Christoffer Bergvall; Stephen Wise; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; polycyclic aromatic hydrocarbon; PAH; benzo[a]pyrene; B[a]P; carcinogenicity; cancer risk assessment; complex matrix; automation; hyphenation; multidimensional chromatography; two-dimensional; method translation; online fractionation; benz[j]aceanthrylene; B[j]A; relative potency factor; Analytical Chemistry; analytisk kemi;

    Abstract : One group of organic environmental pollutants which are potentially hazardous to human health is polycyclic aromatic hydrocarbons (PAHs). These compounds consist of two or more benzene rings in their structure among which benzo[a]pyrene (B[a]P) is classified as a human carcinogen. READ MORE

  6. 4. Development of Enhanced Analytical Methodology for Lipid Analysis from Sampling to Detection : A Targeted Lipidomics Approach

    Author : Giorgis Isaac; Jonas Bergquist; Karin Markides; Monica Waldebäck; William Christie; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Analytical chemistry; electrospray ionization; lipids; liquid chromatography; mass spectrometry; pesticides; phosphatidylcholine; pressurized fluid extraction; sphingomyelin; sulfatides; Analytisk kemi; Analytical chemistry; Analytisk kemi;

    Abstract : This thesis covers a wide range of analytical method development for lipid analysis in complex biological samples; from sample preparation using pressurized fluid extraction (PFE) and separation with reversed phase capillary liquid chromatography (RP-LC) to detection by electrospray ionization mass spectrometry (ESI/MS) and tandem MS.The requirements for fast, reliable and selective extraction methods with minimal usage of solvents have accelerated the development of new extraction techniques. READ MORE

  7. 5. Essentially Lipids : Analytical methods for the characterization of lipid materials

    Author : Petter Olsson; Bengt Herslöf; Jan Holmbäck; Torgny Fornstedt; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Lipids; Chromatography; HPLC; Charged Aerosol Detection; Evaporative light scattering detection; mass spectrometry; Analytical Chemistry; analytisk kemi;

    Abstract : This thesis describes analytical methods for chromatographic characterizations of lipids in biological and technical systems.Lipids are a group of compounds with a central role in all known forms of life. In addition to the biological roles, lipids are also components in many products of our daily usage. READ MORE