Search for dissertations about: "open Source"

Showing result 21 - 25 of 415 swedish dissertations containing the words open Source.

  1. 21. Open tibial fractures in Sweden

    Author : Ulrika Tampe; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Open tibial fractures are serious injuries, challenging both for patients and doctors. For the patients, personal, psychological and physical costs are enormous. For healthcare and society, open tibial fractures are injuries that require resources at a high cost. The literature on Swedish patients with open tibial fractures is sparse. READ MORE

  2. 22. MMIC-based Low Phase Noise Millimetre-wave Signal Source Design

    Author : Thi Ngoc Do Thanh; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; millimetre-wave; MMIC; low frequency noise; phase noise; GaN HEMT; signal source; D-band; InP DHBT; deposition method.; SiGe BiCMOS; frequency multiplier; VCO; passivation;

    Abstract : Wireless technology for future communication systems has been continuously evolving to meet society’s increasing demand on network capacity. The millimetre-wave frequency band has a large amount of bandwidth available, which is a key factor in enabling the capability of carrying higher data rates. READ MORE

  3. 23. Functional and Molecular Characterization of BRCA1 and BRCA2 Associated Breast Cancer

    Author : Johan Vallon-Christersson; Bröstcancer-genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; onkologi; cancer; Cytologi; cancerology; Cytology; BioArray Software Environment; BASE; Software; Open-source; Copy number; Gene expression; Microarray; BRCA2; BRCA1; Breast cancer; Hereditary cancer; oncology;

    Abstract : This doctoral dissertation is based on five appended papers primarily concerned with three main topics, namely: the functional characterization of specific and clinically relevant perturbations found in BRCA1 ? one of the major breast cancer susceptibility genes; the use of microarray technologies for molecular characterization of hereditary breast tumor samples from a genomic perspective; and finally, the development of software to address some of the logistical problems of data analysis and management that arise when utilizing microarrays. Results obtained from the work presented herein demonstrate the following: that transcription az says can aid in the characterization of C-terminal missense mutations but that it may not be possible to unambiguously characterize variants with a yeast-based assay alone; that a naturally occurring C-terminal germline mutation in BRCA1 encodes a protein with apparent temperature-dependant functional properties; that open-source software can provide comprehensive solutions to meet data management needs of microarray experimenters; that BRCA1 and BRCA2 associated breast tumors exhibit markedly different copy number aberrations when compared to each other as well as to sporadic tumors; and that gene expression profiling in BRCA1 and BRCA2 associated breast tumors reveals specific gene expression patterns. READ MORE

  4. 24. Development of an Interactive E-learning Management System (e-LMS) for Tanzanian Secondary Schools

    Author : Ellen Kalinga; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; ICT; Tanzania; Secondary Schools; e-Learning; Software Engineering; UML; OOSA D; MDA; PIM; PSM; LMS; Open Source; Customization; Replication; Mirroring; Focus Group Discussion; mode 2; Triple Helix Processes;

    Abstract : e-Learning, defined as the use of information and communications technology (ICT) for supporting the educational process, has motivated Tanzania to apply ICT in its education systems. Tanzanian secondary schools which are geographically and socially isolated face a number of problems, including a way to get learning materials. READ MORE

  5. 25. Exploring genetic heterogeneity in cancer using high-throughput DNA and RNA sequencing

    Author : Erik Fasterius; Cristina Al-Khalili Szigyarto; Mathias Uhlén; Peter-Bram ’t Hoen; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; Biotechnology; bioinformatics; RNA-seq; WGS; WES; systems biology; variant analysis; single nucleotide variant; gene expression; machine learning; clustering; open source; R; bioconductor; Python; Bioteknologi; Biotechnology;

    Abstract : High-throughput sequencing (HTS) technology has revolutionised the biomedical sciences, where it is used to analyse the genetic makeup and gene expression patterns of both primary patient tissue samples and models cultivated in vitro. This makes it especially useful for research on cancer, a disease that is characterised by its deadliness and genetic heterogeneity. READ MORE