Search for dissertations about: "open thoracic surgery"

Showing result 6 - 10 of 13 swedish dissertations containing the words open thoracic surgery.

  2. 6. Pathophysiological and Histomorphological Effects of One-Lung Ventilation in the Porcine Lung

    Author : Alf Kozian; Göran Hedenstierna; Thomas Hachenberg; Filip Freden; Sten Walther; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alveolar Recruitment Manoeuvre; One-Lung Ventilation; Lung Protective Ventilation; Tidal Volume; Computed Tomography; Tidal Recruitment; Animal Model; Open Thoracic Surgery; Ventilation Perfusion Distribution; Single Photon Emission Computed Tomography; Diffuse Alveolar Damage; Medical laboratory science; Medicinsk laboratorievetenskap; Anestesiologi; Anaesthesiology;

    Abstract : Thoracic surgical procedures require partial or complete airway separation and the opportunity to exclude one lung from ventilation (one-lung ventilation, OLV). OLV is commonly associated with profound pathophysiological changes that may affect the postoperative outcome. READ MORE

  4. 7. The Immune Response to One-Lung Ventilation : Clinical and Experimental Studies

    Author : Thomas Schilling; Göran Hedenstierna; Hans Hedenström; Thomas Hachenberg; Sven-Erik Ricksten; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; One-lung ventilation; open thoracic surgery; ventilation-induced lung injury; alveolar immune response; bronchoalveolar lavage; propofol; desflurane; cytokines; animal model; mRNA; RT-PCR; Medical laboratory science; Medicinsk laboratorievetenskap; anestesiologi; Anaesthesiology;

    Abstract : One-lung ventilation (OLV) as an established procedure during thoracic surgery may be injurious in terms of increased mechanical stress characterised by alveolar cell stretch and overdistension, increased cyclic tidal recruitment of alveolar units, compression of alveolar vessels and increased pulmonary vascular resistance. This may result in ventilation-induced lung injury with pro-inflammatory cytokine production, leukocyte recruitment and neutrophil-dependent tissue destruction. READ MORE

  5. 8. Negative Pressure Wound Therapy - Effects on Sternotomy Wounds and the Intrathoracic Organs

    Author : Christian Torbrand; Lund Oftalmologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NPWT; negative pressure; vacuum-assisted closure; sternotomy wounds; deep sternal wound infection; mediastinitis; thoracic surgery; pressure transduction; neurohormones; neuropeptides; total heart volume variation; cardiac output; wound contraction; macrodeformation;

    Abstract : Negative pressure wound therapy (NPWT) has been widely adopted for the treatment of deep sternal wound infections due to its excellent clinical outcome. However, the mechanisms of action and effects on hemodynamics have not been thoroughly elucidated. READ MORE

  6. 9. Gas Embolism in Laparoscopic Liver Surgery

    Author : Diddi Fors; Sten Rubertsson; Dag Arvidsson; Tor Inge Tønnessen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gas embolism; laparoscopic liver; CVP; PEEP; high frequency jet ventilation; cardiopulmonary physiology; carbon dioxide; Anaesthesiology and Intensive Care; Anestesiologi och intensivvård;

    Abstract : Laparoscopic liver surgery is complicated due to the structure of this organ with open sinusoids. A serious disadvantage is the risk of gas embolism (GE) due to CO2 pneumoperitoneum. CO2 can enter the vascular system through a wounded vein. A common opinion is that gas fluxes along a pressure gradient, e. READ MORE

  7. 10. Carbon dioxide de-airing in cardiac surgery

    Author : Peter Svenarud; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Carbon dioxide; De-airing; Air embolism; Cardiac surgery; Insufflation device; Microemboli; Transesophageal echocardiography;

    Abstract : Background: The risks connected with the presence of air microemboli in open-heart surgery, have recently been emphasized by reports that their number is correlated with the degree of postoperative neuropsychological disorder. Insufflation of carbon dioxide (C02) into the chest wound is used in open-heart surgery to de-air the heart and great vessels. READ MORE