Search for dissertations about: "opsonization"

Showing result 1 - 5 of 19 swedish dissertations containing the word opsonization.

  1. 1. C-reactive protein (CRP) and anti-CRP autoantibodies in systemic lupus erythematosus a study on the occurrence and clinical implications of anti-CRP antibodies and CRP-mediated complement activation

    University dissertation from Institutionen för molekylär och klinisk medicin

    Author : Christopher Sjöwall; Linköpings universitet.; Linköpings universitet.; [2006]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; autoantibodies; complement activation; C-reactive protein; cytokines; immune complex; immunoregulation; opsonization; systemic lupus erythematosus; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Internal medicine Rheumatology; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Invärtesmedicin Reumatologi;

    Abstract : Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by production of a wide range of autoantibodies, multiple organ involvement and by local formation or tissue deposition of immune complexes (ICs) in the inflamed organs. In contrast to most systemic inflammatory conditions, and despite raised levels of pro-inflammatory cytokines, SLE flares are rarely reflected by elevated C-reactive protein (CRP), an important acute-phase reactant in man with homologs in vertebrates and several invertebrates. READ MORE

  2. 2. Effects of Complement Opsonization of HIV on Dendritic Cells and Implications for the Immune Response

    University dissertation from Linköping : Linköping University Electronic Press

    Author : Rada Ellegård; Linköpings universitet.; Linköpings universitet.; [2018]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; HIV; dendritic cells; complement; innate immune response; TLR signaling; T cell activation; NK cells; inflammation; antiviral response; immune evasion;

    Abstract : Dendritic cells are key players during HIV pathogenesis, and shape both the immediate immune response at the site of infection as well as directing the adaptive immune response against the virus. HIV has developed a plethora of immune evasion mechanisms that hijack dendritic cell functions, suppressing their ability to mount an accurate immune response and exploiting them for efficient viral transfer to target T cells. READ MORE

  3. 3. Invasive group A streptococcal infection : host and pathogen interactions

    University dissertation from Stockholm : Karolinska Institutet, Department of Immunology, Microbiology, Pathology and Infectious Diseases

    Author : Björn K.G. Eriksson; Karolinska Institutet.; Karolinska Institutet.; [1999]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Group A streptococci; invasive infections; erysipelas; Streptococcal Toxic Shock Syndrome STSS ; epidemiology; M1 serotype streptococcal pyrogenic exotoxins Spe ; SpeA; toxin neutralization; opsonization;

    Abstract : Invasive group A streptococcal (GAS) infections were studied in 229 patients with a clinical diagnosis of erysipelas and 151 patients with GAS bacteremia, respectively. Beta-hemolytic streptococci were identified in about a third of the erysipelas patients, mostly group A, whereas group G streptococci were identified in about half as many episodes. READ MORE

  4. 4. Complement activation - good or evil in HIV-1 infection? interaction of free and complement opsonized HIV-1 with monocyte derived dendritic cells and immune cells in the cervical mucosa

    University dissertation from Linköping : Linköping University Electronic Press

    Author : Veronica Tjomsland; Linköpings universitet.; Linköpings universitet.; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Worldwide, the heterosexual route is the most common mode of sexual transmission of HIV-1 and women are particularly susceptible to this infection. After penetration of the mucosal epithelium HIV-1 interacts with potential target cells, i.e. dendritic cells (DCs) and CD4+ T cells. READ MORE

  5. 5. Cell death and clearance - studies of human neutrophils from blood and tissue

    University dissertation from Linköping : Linköping University Electronic Press

    Author : Karin Christenson; Göteborgs universitet.; Gothenburg University.; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neutrophils; apoptosis; transmigration; phagocytes;

    Abstract : Neutrophils are phagocytic cells that typically migrate from circulation to tissues in order to combat microbial invasion. The journey from blood to tissue involves mobilization of intracellular organelles which results in modifications of surface markers (e.g. READ MORE