Search for dissertations about: "optimality theory"

Showing result 1 - 5 of 59 swedish dissertations containing the words optimality theory.

  1. 1. Optimisation of Clinical Trials using Bayesian Decision Theory

    Author : Sebastian Jobjörnsson; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; decision theory; drug regulation; ; Bayesian statistics; subgroup analysis; clinical trials; health economics; multiple testing; decision theory;

    Abstract : A decision maker confronted with the task of designing a clinical trial has to consider a multitude of aspects. Large trials lead to more evidence,which in turn makes it less likely that harmful decisions are taken when deciding on future treatments for patients. READ MORE

  2. 2. Multivariate Aspects of Phylogenetic Comparative Methods

    Author : Krzysztof Bartoszek; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; General Linear Model; Ornstein-Uhlenbeck process; Multivariate phylogenetic comparative method; Evolutionary model; Adaptation; Optimality; Measurement error; Regression; Adaptation; Major-axis regression; Reduced major-axis regression; Structural equation; Allometry; Phylogenetic inertia; Allometry;

    Abstract : his thesis concerns multivariate phylogenetic comparative methods. We investigate two aspects of them. The first is the bias caused by measurement error in regression studies of comparative data. We calculate the formula for the bias and show how to correct for it. READ MORE

  3. 3. Optimal Design and Inference for Correlated Bernoulli Variables using a Simplified Cox Model

    Author : Daniel Bruce; Hans Nyquist; Werner G. Müller; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cox binary model; correlated binary data; log-odds ratio; D-optimality; E-optimality; power maximization; efficiency; Statistics; Statistik; statistik; Statistics;

    Abstract : This thesis proposes a simplification of the model for dependent Bernoulli variables presented in Cox and Snell (1989). The simplified model, referred to as the simplified Cox model, is developed for identically distributed and dependent Bernoulli variables. READ MORE

  4. 4. Optimal Design of Experiments for the Quadratic Logistic Model

    Author : Ellinor Fackle Fornius; Hans Nyquist; Christos Kitsos; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Logistic regression; D-optimality; c-optimality; Canonical design space; Maximum likelihood estimation; Sequential design; Stochastic approximation; Statistics; Statistik; statistik; Statistics;

    Abstract : Optimal design of experiments for binary data is the topic of this thesis. A particular logistic model including a quadratic term in the linear predictor is considered. Determining an optimal design for this model is complicated by the fact that the optimal design is dependent on the unknown true parameters. READ MORE

  5. 5. Optimality conditions for synthetic estimators

    Author : Mats Wiklund; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; sunthetic; post stratified and composite estimator and small area statistics; sunthetic;

    Abstract : .... READ MORE