Search for dissertations about: "optimising dose"

Showing result 1 - 5 of 9 swedish dissertations containing the words optimising dose.

  2. 1. Optimising Radiotherapy in Rectal Cancer Patients

    Author : Calin Radu; Bengt Glimelius; Åke Berglund; Lars Påhlman; Ragnar Hultborn; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rectal cancer; locally advanced; radiotherapy; FDG-PET; peripheral boost; protons; quality-of-life; Oncology; Onkologi;

    Abstract : Rectal cancer is the eight most common cancer diagnosis in Sweden in both men and women, with almost 2000 new cases per year. Radiotherapy, which is an important treatment modality for rectal cancer, has evolved during the past decades. READ MORE

  4. 2. Small-Scale Absorbed Dose Modelling in Selective Internal Radiation Therapy : Microsphere Distribution in Normal Liver Tissue

    Author : Jonas Högberg; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; clusters; dosimetry; heterogeneity; liver; microspheres; radioembolisation; simulations; SIRT; surgery; yttrium-90;

    Abstract : Radioembolisation (RE), with yttrium-90 (90Y) labelled microspheres, is an increasingly common treatment method for unresectable liver tumours. The tolerable mean absorbed dose for normal liver (NL) tissue is higher in RE than in External Beam Radiation Therapy (EBRT); absorbed dose heterogeneity is thought to be one important reason, together with a low absorbed dose rate, but the knowledge of microsphere distributions is limited. READ MORE

  5. 3. Optimising External Beam Radiotherapy for Prostate Cancer. Advances in Treatment Planning

    Author : Vilberg Jóhannesson; Systemisk strålterapi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : BackgroundRadiotherapy (RT) is an effective treatment option for prostate cancer (PCa). The evolution of new treatment planning techniques, advanced imaging and accelerator design has enabled precise treatment delivery. READ MORE

  6. 4. Estimation of Dosing Strategies for Individualisation

    Author : Siv Jönsson; Mats O. Karlsson; Leon Aarons; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; Dosing strategy; Individualisation; Pharmacokinetic; Pharmacodynamic; Modeling; NONMEM; Decision making; Farmaceutisk biovetenskap; Biopharmacy; Biofarmaci;

    Abstract : To increase the proportion of patients with successful drug treatment, dose individualisation on the basis of one or several patient characteristics, a priori individualisation, and/or on the basis of feedback observations from the patient following an initial dose, a posteriori individualisation, is an option. Efficient tools in optimising individualised dosing strategies are population models describing pharmacokinetics (PK) and the relation between pharmacokinetics and pharmacodynamics (PK/PD). READ MORE

  7. 5. Temporomandibular joint imaging using cone-beam computed tomography

    Author : Durer Iskanderani; Reinhilde Jacobs; Malmö universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Cone-beam computed tomography (CBCT) is one of the most revolutionary innovations in dentistry, and was introduced into the dental field two decades ago as a three-dimensional (3D) imaging modality. Since then, it has gained general clinical acceptance, and is widespread among many dental specialties. READ MORE