Search for dissertations about: "oral anticoagulant drug"

Showing result 1 - 5 of 8 swedish dissertations containing the words oral anticoagulant drug.

  1. 1. Prevalence of drug-drug interactions and clinical relevance for treatment with oral anticoagulants

    Author : Johan Holm; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The aim of this thesis was to describe prevalences and frequencies of potential DDIs in the Swedish outpatient population, and the clinical effects in treatment with oral anticoagulants. Two cross-sectional studies were conducted to establish the prevalence and frequency of potential DDIs among Swedish outpatients. READ MORE

  2. 2. Intracerebral hemorrhage and antithrombotic drugs - clinical aspects and prognostic outcomes

    Author : Trine Apostolaki-Hansson; Lund Neurologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; intracerebral hemorrhage; oral anticoagulant drug; reversal therapy; prognosis; survival; functional outcome; antithrombotic drugs;

    Abstract : .... READ MORE

  3. 3. Effects of direct oral anticoagulant treatment on hemostasis in patients with atrial fibrillation

    Author : Viktor Schutz Taune; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The direct oral anticoagulants (DOAC) – dabigatran, rivaroxaban, apixaban and edoxaban – were approved without the need for routine monitoring. However, in parallel with clinical implementation, studies on how to measure the effect of DOACs have become a research area of increasing interest during the last decade. READ MORE

  4. 4. The in-vitro and in-vivo metabolism of the oral anticoagulant phenprocoumon as influenced by genetic polymorphisms of cytochrome P4502C9

    Author : Mike Ufer; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Drug metabolism; cytochrome P450; genetic polymorphism; genotyping; CYP2C9; phenprocoumon; warfarin; acenocoumarol; oral anticoagulants;

    Abstract : Oral anticoagulants are widely used for the prevention of thromboembolic disorders. Warfarin (WA) is most commonly used world-wide, while phenprocoumon (PPC) is the first-line anticoagulant in some European countries including Germany. Each anticoagulant exists in two different enantiomeric forms and is administered orally as a racemate. READ MORE

  5. 5. Two worlds, one goal : A Clinician’s Perspective on Laboratory Analyses in Anticoagulant Treatment

    Author : Kerstin Arbring; Tomas Lindahl; Srinivas Uppugunduri; Margareta Holmström; Gerd Lärfars; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anticoagulants; Warfarin; DOAC; PT-INR; VKORC1;

    Abstract : Almost precisely a century ago, in the 1920s and 1930s, cattle bled to death in North America after being fed moldy hay containing sweet clover, the yellow Melilotus officinalis, and the white Melilotus albus. The toxic substance in the hay inhibiting blood coagulation was identified and named dicumarol. READ MORE