Search for dissertations about: "oral keratinocytes"
Showing result 6 - 10 of 15 swedish dissertations containing the words oral keratinocytes.
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6. Effects of 5-fluorouracil on oral barrier functions
Abstract : Many anticancer drugs, e.g. 5-fluorouracil (5-FU), may cause oral mucositis and ulcerations. These adverse reactions can be severe and debilitating to the patient, and adjustment of the cancer treatment may be necessary. READ MORE
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7. Invariant T cell subsets in immune defense of oral mucosa and skin
Abstract : Innate-like T lymphocytes such as mucosa-associated invariant T (MAIT) cells and invariant natural killer T (iNKT) cells recognize antigens presented by MR1 and CD1d molecules, respectively. As MR1 presents microbial riboflavin metabolite antigens, and CD1d presents endogenous or microbial glycolipid antigens, MAIT cells and iNKT cells survey the non-protein fraction of the potential antigenic universe. READ MORE
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8. Modeling of multi-step oral carcinogenesis in vitro : assessment of growth, differentiation and apoptosis markers
Abstract : Human oral mucosa, especially the buccal epithelium, is worldwide a common site for cancer. Cancer development frequently results in inactivation of tumor suppressor p53, a central regulator of growth and programmed cell death, and deregulated expression of structural elements like cytokeratins. READ MORE
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9. Toxicity of smokeless tobacco in human oral epithelium with emphasis on carcinogen metabolism and regulation of programmed cell death
Abstract : The oral mucosa is globally a common site for cancer development. Primary risk factors include tobacco smoking and alcohol consumption whereas the contribution from usage of smokeless tobacco remains debated. READ MORE
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10. Novel innate immune functions of saliva
Abstract : The innate immune system in humans has succeeded in developing numerous mechanisms against the injurious effects of bacteria, along with their toxins as a result of several thousand years of co-evolution. The oral mucosal surface represents such a unique environment, where despite being constantly exposed to microbes and their products, overt infection and damage is a rarity. READ MORE