Search for dissertations about: "organ culture"

Showing result 16 - 20 of 111 swedish dissertations containing the words organ culture.

2. 16. Who is Who in the Adipose Organ : A look at the Heterogeneity of Adipocyte Biology

   Author : Jasper de Jong; Jan Nedergaard; Christian Wolfrum; Stockholms universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adipose tissue; Adipocyte; Brown; White; Brite Beige; Physiology; fysiologi; Physiology;

   Abstract : The increasing prevalence of obesity and related health complications, such as type 2 diabetes, cardiovascular disease and cancer, demands thorough investigation of the underlying processes. One of the key tissues investigated in this context is adipose tissue. READ MORE

4. 17. Novel culture systems to model testicular function and organization

   Author : João Pedro Alves Lopes; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : In vitro systems to model the testicular microenvironment are required to study physiology and pathology of the testis, the gonadotoxic effect of environmental and pharmaceutical chemicals, as well as to explore the mechanisms ruling spermatogonial stem cell (SSC) self-renewal and differentiation. The knowledge produced in in vitro experiments, using animal, but most importantly utilizing human models, will contribute to the discovery of safe medical treatments and might provide translational tools to treat male infertility problems. READ MORE

5. 18. Human ovarian follicles and oocytes : collection, cryopreservation, culture and gene expression

   Author : Pu Zhang; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Ovarian follicle; oocyte; follicular aspirate; organ culture; cAMP; cGMP; cryopreservation; microarray; human gene expression; embryonic stem cell; preimplantation;

   Abstract : Infertility affects approximately 15% of couples globally. The most effective treatment today is in vitro fertilization. However, not all couples can be helped with the current techniques. To achieve better success, techniques of storage and in vitro maturation of ovarian follicles have to be improved. READ MORE

6. 19. Calcium channel activity and force regulation in smooth muscle: Effects of polyamines and growth stimulation

   Author : Maria Gomez; Kardiovaskulär forskning - immunitet och ateroskleros; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; verapamil; tissue culture; portal vein; patch-clamp; calcium; spermidine; spermine; polyamines; excitation-contraction; smooth muscle; calcium channel; ionomycin.; Physiology; Fysiologi;

   Abstract : The initial signal for contraction in smooth muscle is an increase in [Ca2+]i. Ca2+ ions can either enter the cytosol from the extracellular medium or be released from intracellular stores. Voltage-operated Ca2+ channels (VOC) play a dominant role in the activation of smooth muscle contraction. READ MORE

7. 20. Distribution and function of TRP ion channels in primary sensory neurons

   Author : Helena Sturesson; Avdelningen för klinisk kemi och farmakologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurofysiologi; neuropsykologi; histokemi; cytokemi; vävnadskultur; Neurology; neuropsychology; neurophysiology; Neurologi; tissue culture; histochemistry; cytochemistry; Histology; Skin; Immunohistochemistry; Cannabinoid receptor 1 CB1 ; Pain; Primary sensory neurons; TRP ion channels; Pharmacological sciences; pharmacognosy; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi; Histologi;

   Abstract : It is frequently argued that cannabinoids exert part of their analgesic and anti-inflammatory effects via activation of the cannabinoid CB1 receptor located on TRPV1-expressing primary sensory nerve fibres in peripheral tissues. However, we find no evidence of CB1 receptor immunoreactivity on nerve fibres in rat or mouse hindpaw skin and mesenteric artery. READ MORE