Search for dissertations about: "organ dose"

Showing result 11 - 15 of 156 swedish dissertations containing the words organ dose.

  2. 11. Modulating Organ Dysfunction in Experimental Septic Shock : Effects of Aminoglycosides, Antiendotoxin Measures and Endotoxin Tolerance

    Author : Markus Castegren; Jan Sjölin; Claes Frostell; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lipopolysaccharide; animal model; pig; tobramycin; endotoxin elimination; immunoparalysis; secondary sepsis; Infectious diseases; Infektionssjukdomar; Infektionssjukdomar; Infectious Diseases;

    Abstract : Sepsis is a common diagnose in the intensive care population, burdened with a high mortality. The systemic inflammatory reaction underlying the development of septic organ dysfunction can be modeled using Gram-negative bacterial lipopolysaccharide, endotoxin. READ MORE

  4. 12. Dose-response modeling : evaluation, application, and development of procedures for benchmark dose analysis in health risk assessment of chemical substances

    Author : Salomon Sand; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Risk assessment; dose-response; benchmark; BMD;

    Abstract : In this thesis, dose-response modeling and procedures for benchmark dose (BMD) analysis in health risk assessment of chemical substances have been investigated. The BMD method has been proposed as an alternative to the NOAEL (no-observedadverse- effect-level) approach in health risk assessment of non-genotoxic agents. READ MORE

  5. 13. Radiation dose and related risk in interventional cardiology

    Author : Angeliki Karambatsakidou; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cardiac catheterization procedures are classified as high radiation dose procedures, European Directive 2013/59/Euratom, and may result in skin injuries (deterministic effects) and/or increased cancer risk (stochastic effects). The radiation-induced effects can be expressed differently depending on whether the patient is a child or an adult. READ MORE

  6. 14. Radiotherapy for head and neck cancer : costs and benefits of time, dose and volume

    Author : Karin Söderström; Björn Zackrisson; Werner Dubrowsky; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; radiotherapy; head and neck cancer; adjuvant treatment; accelerated fractionation; biomedicinsk strålningsvetenskap; Biomedical Radiation Science;

    Abstract : Background In the treatment of head and neck cancers (HNCs), radiotherapy (RT) has the advantage of organ preservation compared to surgery. However, treatment toxicities associated with RT can affect important functions for everyday life, both in the acute and late stage. READ MORE

  7. 15. Clinical and experimental studies of organ-specific autoimmune diseases : With special reference to Addison's disease and autoimmune hepatitis : by Gennet Gebre-Medhin

    Author : Gennet Gebre-Medhin; Uppsala universitet; []
    Keywords : Medical sciences; Addison s Disease; replacement therapy; DHEA; autoimmune hepatitis; APS I; autoantigen; cytochrome P4501A2; aromatic L-amino acid decarboxylase; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Abstract : Organ-specific autoimmunity constitutes a large health problem, where both the clinical management and our understanding of the pathogenetic mechanisms need to improve. Women with Addison's disease have abnormally low levels of dehydroepiandrosterone (DHEA), its sulphate ester (DHEA-S) and androgens relative to age, and many patients complain of physical and mental fatigue and low stress tolerance. READ MORE