Search for dissertations about: "organic acid anhydride"

Showing result 1 - 5 of 9 swedish dissertations containing the words organic acid anhydride.

  2. 1. Metabolism and Biological Monitoring of Organic Acid Anhydrides

    Author : Christian Lindh; Avdelningen för arbets- och miljömedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rats; human; distribution; analysis; biological monitoring; autoradiography; adducts; hemoglobin; plasma; urine; Hexahydrophthalic anhydride; methyltetrahydrophthalic anhydride; guinea pigs; Occupational health; industrial medicine; Yrkesmedicin; arbetsmiljömedicin;

    Abstract : The aim of this thesis was to describe the metabolism and to develope methods for biological monitoring for two organic acid anhydrides (OAAs), namely hexahydrophthalic anhydride (HHPA) and methylhexa-hydrophthalic anhydride (MHHPA). The OAAs are reactive, low molecular weight chemicals used in vast quantities in the industry. READ MORE

  4. 2. Protein adducts in plasma as biomarkers of exposure to and risk of organic acid anhydrides

    Author : Seema Rosqvist; Neurokirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; GC-MS; IgG; IgE; exposure-response; serum albumin; biological monitoring; Hexahydrophthalic anhydride; methylhexahydrophthalic anhydride; OEL; Occupational health; industrial medicine; Yrkesmedicin; arbetsmiljömedicin;

    Abstract : Organic acid anhydrides (OAAs) are important industrial chemicals but also potent inducers of airways diseases. Many exposed workers develop specific IgE and IgG antibodies. Hexahydrophthalic anhydride (HHPA) and methylhexahydrophthalic anhydride (MHHPA) are two particularly sensitising OAAs. READ MORE

  5. 3. Syntheses of some tri- and tetracyclic heterocycles containing an indole moiety

    Author : Robert Engqvist; jan Bergman; Victor Snieckus; Södertörns högskola; Karolinska Institutet; Karolinska Institutet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Alkaloid; drug development; heterocycles; indole; metabolite; synthesis; X-ray crystallography;

    Abstract : This thesis deals with the development of new synthetic methods leading to fused tri- and tetracyclic heterocycles, many of which have interesting biological activity such as antiviral and DNA intercalating properties. The reactions between isatins and 2-aminobenzylamine in acetic acid can give, depending on the conditions, either complex spirooxindoles or indolo[3,2-c]quinolin-6-ones. READ MORE

  6. 4. Protein adducts of hexahydrophthalic anhydride- chemical structures and biomarkers

    Author : Monica Kåredal; Avdelningen för arbets- och miljömedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; arbetsmiljömedicin; Yrkesmedicin; industrial medicine; Occupational health; nasal lavage; mass spectrometry; biomarker; human serum albumin; hemoglobin; Hexahydrophthalic anhydride; adducts;

    Abstract : Organic acid anhydrides (OAAs) are low molecular weight chemicals used in the industry for manufacturing of plastics such as epoxy resins. Exposure to these chemicals may lead to symptoms from the eyes and the respiratory tract in form of conjunctivitis, rhinitis and asthma. READ MORE

  7. 5. Aerosols of Isocyanates, Amines and Anhydrides : Sampling and Analysis

    Author : Jakob Dahlin; Gunnar Skarping; Robert P. Streicher; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; isocyanate; amine; aminoisocyanate; organic acid anhydride; denuder; impactor; impinger; air sampling; LC-MS; LC-CLND; di-n-butylamine; DBA; thermal degradation; aerosol; particles; TDI; MDI; HDI; ICA; MIC; IPDI; exposure; occupational health; Analytical chemistry; Analytisk kemi; Analytical Chemistry; analytisk kemi;

    Abstract : This thesis presents methods for air sampling and determination of isocyanates, amines, aminoisocyanates and anhydrides. These organic compounds are generated during thermal degradation of polymers such as polyurethane (PUR) or epoxy.Isocyanates, amines and anhydrides are airway irritants known to cause occupational asthma. READ MORE