Search for dissertations about: "organic acid anhydrides"

Showing result 1 - 5 of 6 swedish dissertations containing the words organic acid anhydrides.

  2. 1. Relationship between chemical structure and airway sensitizing potential for organic acid anhydrides : an animal model

    Author : Xing-Dong Zhang; Avdelningen för arbets- och miljömedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sensitization; immunization; predictive testing; low-molecular-weight chemicals; chemical respiratory allergy; hypersensitivity; rats; guinea pigs; structure-activity-relationship; occupational asthma; organic acid anhydrides; IgG1; IgE; Occupational health; industrial medicine; Yrkesmedicin; arbetsmiljömedicin;

    Abstract : Oranic acid anhydrides (OAAs) are important reactive, low-molecular-weight industrial chemicals which induce allergic rhinitis and asthma in exposed subjects. Specific IgE has been demonstrated in a large proportion of OAA-exposed workers. READ MORE

  4. 2. Metabolism and Biological Monitoring of Organic Acid Anhydrides

    Author : Christian Lindh; Avdelningen för arbets- och miljömedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rats; human; distribution; analysis; biological monitoring; autoradiography; adducts; hemoglobin; plasma; urine; Hexahydrophthalic anhydride; methyltetrahydrophthalic anhydride; guinea pigs; Occupational health; industrial medicine; Yrkesmedicin; arbetsmiljömedicin;

    Abstract : The aim of this thesis was to describe the metabolism and to develope methods for biological monitoring for two organic acid anhydrides (OAAs), namely hexahydrophthalic anhydride (HHPA) and methylhexa-hydrophthalic anhydride (MHHPA). The OAAs are reactive, low molecular weight chemicals used in vast quantities in the industry. READ MORE

  5. 3. Aerosols of Isocyanates, Amines and Anhydrides : Sampling and Analysis

    Author : Jakob Dahlin; Gunnar Skarping; Robert P. Streicher; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; isocyanate; amine; aminoisocyanate; organic acid anhydride; denuder; impactor; impinger; air sampling; LC-MS; LC-CLND; di-n-butylamine; DBA; thermal degradation; aerosol; particles; TDI; MDI; HDI; ICA; MIC; IPDI; exposure; occupational health; Analytical chemistry; Analytisk kemi; Analytical Chemistry; analytisk kemi;

    Abstract : This thesis presents methods for air sampling and determination of isocyanates, amines, aminoisocyanates and anhydrides. These organic compounds are generated during thermal degradation of polymers such as polyurethane (PUR) or epoxy.Isocyanates, amines and anhydrides are airway irritants known to cause occupational asthma. READ MORE

  6. 4. Protein adducts in plasma as biomarkers of exposure to and risk of organic acid anhydrides

    Author : Seema Rosqvist; Neurokirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; GC-MS; IgG; IgE; exposure-response; serum albumin; biological monitoring; Hexahydrophthalic anhydride; methylhexahydrophthalic anhydride; OEL; Occupational health; industrial medicine; Yrkesmedicin; arbetsmiljömedicin;

    Abstract : Organic acid anhydrides (OAAs) are important industrial chemicals but also potent inducers of airways diseases. Many exposed workers develop specific IgE and IgG antibodies. Hexahydrophthalic anhydride (HHPA) and methylhexahydrophthalic anhydride (MHHPA) are two particularly sensitising OAAs. READ MORE

  7. 5. Protein Modifications by Low Molecular Weight Chemicals Inducing Airways Diseases

    Author : Marina Jeppsson; Avdelningen för arbets- och miljömedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MSight; hemoglobin human serum albumin; nasal lavage; acrylates; organic acid anhydrides; persulfate; biomarkers adducts; mass spectrometry; MoDetect;

    Abstract : Airways diseases are one of the most common health effects in the western world today. It has been shown that low molecular weight chemicals (LMWC) can cause airways diseases. The mechanisms for these diseases are not well known in most cases. Also, methods for biological monitoring of exposure are not available for many of these LMWC. READ MORE