Search for dissertations about: "organic molecules on surface"
Showing result 1 - 5 of 141 swedish dissertations containing the words organic molecules on surface.
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1. Photochemical Surface Functionalization : Synthesis, Nanochemistry and Glycobiological Studies
Abstract : This thesis mainly deals with the development of photochemical approaches to immobilize carbohydrates on surfaces for glycobiological studies. These approaches have been incorporated into a number of state-of-the-art nanobio-platforms, including carbohydrate microarrays, surface plasmon resonance (SPR), quartz crystal microbalance (QCM), atomic force microscopy (AFM), and glyconanomaterials. READ MORE
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2. Redefining the essential molecular aspects that drive interactions between small molecules and G-quadruplex DNA
Abstract : G-Quadruplex (G4) structures are secondary nucleic acid structures located in guanine-rich regions of DNA and RNA sequences, involved in gene regulation and cellular maintenance. Efforts to target G4s in a therapeutic setting are scarce, mainly due to vague details about the binding interactions between the ligands and the G4 structure combined with the lack of emphasis on drug-like properties early in the ligand development process. READ MORE
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3. Towards novel antibacterials : Synthesis and identification of natural product inspired inhibitors of Chlamydia trachomatis and development of chemical probes targeting virulence of Pseudomonas aeruginosa
Abstract : Antibiotic resistance has evolved significantly to become one of the serious threats to public health today. Yet, the pipeline of new antibiotics is drying up and is lagging behind the challenging needs. READ MORE
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4. Design and construction of organic molecules for use in molecular electronics : rigid molecules ordered on a surface through self-assembly
Abstract : .... READ MORE
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5. Carbohydrate-Based Inhibitors of Pathogen Adhesion to Cell Surface Glycoconjugates
Abstract : The fact that a growing number of pathogens develop resistance against traditional treatment is a growing medical problem. Infections, which until now have been harmless, might turn into life threatening diseases. These problems have led to an intensified search for alternative treatments. Analogs of cell surface glycoconjugates are an alternative. READ MORE