Search for dissertations about: "organic"

Showing result 1 - 5 of 2635 swedish dissertations containing the word organic.

  1. 1. Engineering Candida antarctica Lipase A for Enantioselective Transformations in Organic Synthesis Design, Immobilization and Organic Solvent Screening of Smart Enzyme Libraries

    University dissertation from Stockholm : Department of Organic Chemistry, Stockholm University

    Author : Ylva Wikmark; Stockholms universitet.; [2015]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Candida antarctica Lipase A; protein engineering; enzyme libraries; enzyme immobilization; biocatalysis; Organic Chemistry; organisk kemi;

    Abstract : The use of enzymes as catalysts in organic synthesis constitutes an attractive alternative to conventional chemical catalysis. Enzymes are non-toxic and biodegradable and they can operate under mild reaction conditions. READ MORE

  2. 2. Organic Reactions i Organised Media

    University dissertation from Stockholm : Department of Organic Chemistry, Stockholm University

    Author : TOMASZ WITULA; [2007]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; nucleophilic substitution; mesoporous material; microemulsion; silica; lipase; Liquid crystal; alumina; entrapment.; heterogenized; titania; organic synthesis;

    Abstract : A common problem in synthetic organic chemistry is reactant incompatibility between lipophilic organic compounds and inorganic salts. The thesis reports an investigation of some organic reactions, involving incompatible substrate and nucleophile, performed in liquid crystalline phases and also in slurries of mesoporous materials with different symmetry. READ MORE

  3. 3. Synthesis of Organic Compounds for Nuclide Therapy Derivatives of Carboranes, 9-Aminoacridine and Anthracyclines

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Senait Ghirmai; Uppsala universitet.; [2004]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; 9-Aminoacridin; Carborane; Daunorubicin; Doxorubicin; BNCT; Iodine-125; Organisk kemi; NATURAL SCIENCES Chemistry Organic chemistry; NATURVETENSKAP Kemi Organisk kemi;

    Abstract : This thesis addresses the synthesis of organic compounds, some of them are derivatives of compounds with DNA binding properties, for potential use in targeted nuclide therapy. The compounds synthesized therefore also need to contain potent nuclides. READ MORE

  4. 4. Structure-Based Design and Synthesis of Protease Inhibitors Using Cycloalkenes as Proline Bioisosteres and Combinatorial Syntheses of a Targeted Library

    University dissertation from Institutionen för fysik, kemi och biologi

    Author : Fredrik Thorstensson; Linköpings universitet.; Linköpings universitet.; [2005]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; organic chemistry; organic synthesis; combinatorial synthesis; metathesis; olefin metathesis; thrombin; HCV; NS3; protease; proline isosteres; inhibitor; NATURAL SCIENCES Chemistry Organic chemistry Organic synthesis; NATURVETENSKAP Kemi Organisk kemi Organisk syntes;

    Abstract : Structure-based drug design and combinatorial chemistry play important roles in the search for new drugs, and both these elements of medicinal chemistry were included in the present studies. This thesis outlines the synthesis of protease inhibitors against thrombin and the HCV NS3 protease, as well as the synthesis of a combinatorial library using solid phase chemistry. READ MORE

  5. 5. Design and Synthesis of Serine and Aspartic Protease Inhibitors

    University dissertation from Institutionen för fysik, kemi och biologi

    Author : Fredrik Wångsell; Linköpings universitet.; Linköpings universitet.; [2006]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; organic chemistry; organic synthesis; metathesis; HCV; NS3; protease; proline isosteres; inhibitor; aspartic protease inhibitors; hydroxyethylene; NATURAL SCIENCES Chemistry Organic chemistry Organic synthesis; NATURVETENSKAP Kemi Organisk kemi Organisk syntes;

    Abstract : This thesis describes the design and synthesis of compounds that areintended to inhibit serine and aspartic proteases. The first part of the text deals with preparation of inhibitors of the hepatitis C virus (HCV) NS3 serine protease. Hepatitis C is predominantly a chronic disease that afflicts about 170 million people worldwide. READ MORE