Search for dissertations about: "organotypic slice cultures"
Showing result 1 - 5 of 11 swedish dissertations containing the words organotypic slice cultures.
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1. Endoplasmic Reticulum Dynamic Structural Changes in Neurons: The Fission-Fusion Phenomena
Abstract : The endoplasmic reticulum (ER) is crucial for protein synthesis and protein maturation, is involved in cell stress and serves in neurons as the major intracellular Ca2+ store. Neuronal ER forms a continuous network of cisterns and tubules extending from soma to a subset of dendritic spines. READ MORE
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2. Auditory organotypic cultures and progenitor cell implantation
Abstract : According to the WHO, about 5 % of the world’s population suffers from disabling hearing loss. In people above the age of 65 the number is more than 30 %. Common effects of this condition are poor speech discrimination and impaired communication abilities. Patient surveys show that hearing loss often leads to a diminished quality of life. READ MORE
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3. Mechanisms of Ischemic Brain Injury- studies in murine hippocampal slice cultures
Abstract : Cerebral ischemia is a major cause of mortality and morbidity in the western world. Even though much effort has been put into research and development of effective drugs against ischemic damage there is to date no effective pharmacological brain protective treatment. READ MORE
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4. Characterization of hippocampal slice cultures as model systems for neurodegenerative processes in Alzheimer's disease
Abstract : Alzheimer's disease (AD) is the most common cause of dementia and a growing health care problem worldwide. The disease affects different brain regions, including hippocampus, enthorhinal cortex, amygdala, neocortex and certain basal forebrain nuclei. Macroscopically, shrinkage of gyri and widening of sulci characterize the AD brain. READ MORE
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5. Interaction between nerve fiber formation and astrocytes
Abstract : Parkinson’s disease, the second most common neurodegenerative disorder,is characterized by loss of nigrostriatal dopaminergic neurons. To date,there is no defined cause and cure for the disease. An ideal treatmentstrategy is to replace the lost neurons by transplanting fetal dopaminergicneurons to the brain of parkinsonian patients. READ MORE