Search for dissertations about: "origamI"

Showing result 1 - 5 of 12 swedish dissertations containing the word origamI.

  1. 1. Protein Folding and DNA Origami

    Author : Mark Marvin Seibert; David van der Spoel; Helmut Grubmüller; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; protein folding; Molecular Dynamics simulations; DNA origami; Biophysics; Biofysik; Physics with specialization in Biophysics; Fysik med inriktning mot biofysik;

    Abstract : In this thesis, the folding process of the de novo designed polypeptide chignolin was elucidated through atomic-scale Molecular Dynamics (MD) computer simulations. In a series of long timescale and replica exchange MD simulations, chignolin’s folding and unfolding was observed numerous times and the native state was identified from the computed Gibbs free-energy landscape. READ MORE

  2. 2. Nonlinear Programming - Robust Models and Applications

    Author : Christoffer Cromvik; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; optimization; robustness; multi-objective optimization; stochastic mathematical programs with equilibrium constraints; conditional value-at-risk; IMRT; traffic network design; airbag folding; Origami; airbag folding;

    Abstract : The major theme of this thesis is nonlinear programming with an emphasis on applications and robust models. The thesis has two parts. The first three papers comprise the first part. Here, we discuss robustness properties of optimal solutions to a variety of models. READ MORE

  3. 3. Applications of DNA origami encoded nanoscale patterns

    Author : Ferenc Fördös; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Abstract : It was almost four decades ago when the recognition of DNA’s potential use as a programmable, self-assembling building material for nanostructures led to the birth and rapid expansion of the field of DNA nanotechnology, but it was two decades later when the development of the DNA origami technique initiated the widespread use of DNA based nanoconstructs through the simplification of the design process and the reduction of the required control over the quality and stoichiometry of the assembly components by using a single-stranded “scaffold” DNA and a set of “staple” oligonucleotides that “fold” the mentioned scaffold DNA into a predesigned shape by binding different regions of the scaffold strand together. This robust approach not only permitted the construction of intricate two- and three-dimensional structures, but it also allowed the design and fabrication of molecular patterns with unprecedented accuracy as each functionalizible component’s relative position in the DNA origami structure is known to nanometer precision. READ MORE

  4. 4. Numerical Folding of Airbags Based on Optimization and Origami

    Author : Christoffer Cromvik; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : .... READ MORE

  5. 5. Advances in Soft Matter Nanofabrication

    Author : Mehrnaz Shaali; Chalmers University of Technology; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; photolithography; negative e-beam resist; monolayer; confocal microscopy; Teflon AF; KPFM; DNA origami; cells; lipid nanotube; AFM; double bilayer; Phospholipid; electron beam lithography;

    Abstract : The focus of this thesis is placed on the fabrication of engineered nanodevices for the manipulation of soft matter thin films. By combining top-down micro- and nanofabrication approaches with bottom-up self-assembly strategies, new research platforms were developed, tested and characterized. READ MORE