Search for dissertations about: "orphans"

Showing result 6 - 10 of 13 swedish dissertations containing the word orphans.

  2. 6. Childhood trauma and posttraumatic stress disorder : A developmental and cross-cultural approach

    Author : Abdulbaghi Ahmad; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Childhood Trauma; PTSD; Resilience; Cross-Cultural; Kurdistan; Neurovetenskap; Neurology; Neurologi; Child and Youth Psychiatry; Barn- och ungdomspsykiatri;

    Abstract : This thesis aims to identify child-specific cross-cultural protecting and vulnerability factors regarding traumatic experiences and posttraumatic stress reactions. Children between 6-18 years were interviewed from three different socio-cultural backgrounds. READ MORE

  4. 7. Atypical Solute Carriers : Identification, evolutionary conservation, structure and histology of novel membrane-bound transporters

    Author : Emelie Perland; Robert Fredriksson; Helgi Schiöth; Åsa Mackenzie; Sonchita Bagchi; Carsten Uhd Nielsen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Major facilitator superfamily; solute carrier; transporter; protein expression; mRNA expression; phylogenetic clustering; orthologues; co-expression; subcellular location; nutrition.; Neuroscience; Neurovetenskap;

    Abstract : Solute carriers (SLCs) constitute the largest family of membrane-bound transporter proteins in humans, and they convey transport of nutrients, ions, drugs and waste over cellular membranes via facilitative diffusion, co-transport or exchange. Several SLCs are associated with diseases and their location in membranes and specific substrate transport makes them excellent as drug targets. READ MORE

  5. 8. Determining Ligand- and Lipid- Interactions of SLC Transporters

    Author : Yurie Chatzikyriakidou; David Drew; Robert Fredriksson; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Solute carrier transporter; nucleotide-sugar transporter; SLC35; sodium proton exchanger; SLC9B2; thermal stability assay; membrane transport; Synaptic vesicle protein 2; Biochemistry; biokemi;

    Abstract : Solute carrier transporters (SLCs) mediate the inter- and intra- cellular trafficking of a plethora of substrates and are essential to cell homeostasis. Despite their importance to human physiology and their potential as therapeutic targets, many SLCs are considered orphans as the physiological substrate has not been experimentally determined. READ MORE

  6. 9. SOMETHING GOOD BUT NOTHING TO BE PROUD OF : Inheritance and Succession Practices, and Sociopolitical Stakes in Times of Decentralization in Marracuene, Mozambique

    Author : Fernando Matai Manjate; Sten Hagberg; Sverker Finnström; Lars Buur; Uppsala universitet; []
    Keywords : HUMANIORA; HUMANITIES; Inheritance; succession; dispossession; legal pluralism; Marracuene; Mozambique; urbanization; decentralization; anthropology.; Kulturantropologi; Cultural Anthropology;

    Abstract : This ethnographic study focuses on inheritance and succession practices and sociopolitical stakes in present-day Marracuene in southern Mozambique. It explores how in contexts of rapid economic, social, cultural and political change, individuals, social actors and institutions deal with inheritance and succession rights, both when the property holders and incumbents are still alive and after they have passed away. READ MORE

  7. 10. Mass Spectrometric Analysis of Oxylipins : Application to Cytochrome P450-Dependent Metabolism

    Author : Tomas Nilsson; Ernst Oliw; Johan Bylund; Mikael Hedeland; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; epoxyalcohols; fatty acids; hydroperoxides; electrospray ionization; ichthyosis; CYP4; linear ion trap; fragmentation mechanism; Pharmaceutical pharmacology; Farmaceutisk farmakologi; Biochemical Pharmacology; Biokemisk farmakologi;

    Abstract : Cytochrome P450 (CYP) family 4 constitutes monoxygenases responsible for hydroxylation of fatty acids and other lipids. For example, CYP4F3 metabolizes leukotrienes and CYP4F8 prostaglandin H. Importantly, six of the twelve CYP4 enzymes are orphans, i.e. READ MORE