Search for dissertations about: "osteoarthritis rat"
Found 3 swedish dissertations containing the words osteoarthritis rat.
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1. Studies on the level of substance P and calcitonin gene-related peptide in cerebrospinal fluid of pregnant women and patients with chronic pain and in rat brain after spinal cord injury : Special reference to analytical aspects of neuropeptides
Abstract : Substance P (SP) and calcitonin gene-related peptide (CGRP) are sensory peptides known to be involved innociception and inflammatory processes. It is well demonstrated that the two peptides can be released from spinal cord neurons during inflammation and chronic pain induced by peripheral nerve injury. READ MORE
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2. Biochemical biomarkers at the site of inflammation and in peripheral blood
Abstract : Biochemical biomarkers are small molecular species, naturally varying or experimentally induced, which are measurable in body fluids and which may provide alternative or complementary tools to describe disease processes or to assess responses to pharmacological treatment. The focus of this thesis is inflammatory biomarkers, mediators, chemokines and cytokines that attract immune cells and that regulate the course of the inflammatory process at the site of inflammation. READ MORE
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3. Proteasome targeted therapy in arthritis models : effects on pain and inflammation
Abstract : The ubiquitin proteasome system (UPS) regulates numerous cellular functions by selectively degrading cellular proteins. It controls activation of the transcription factor NF-ĸB which is involved in the expression of pro-inflammatory mediators. The UPS regulates neuronal signalling by controlling levels of synaptic proteins during chronic pain. READ MORE
