Search for dissertations about: "osteogenesis"

Showing result 11 - 15 of 35 swedish dissertations containing the word osteogenesis.

  2. 11. Biochemical and functional properties of mammalian bone alkaline phosphatase isoforms during osteogenesis

    Author : Cecilia Halling Linder; Per Magnusson; Elvar Theodorsson; Göran Andersson; Torgny Stigbrand; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The human skeleton is a living and dynamic tissue that constantly is being renewed in a process called bone remodeling. Old bone is resorbed by osteoclasts and new bone is formed by osteoblasts. READ MORE

  4. 12. Prevalence of dentinogenesis imperfecta and dental aberrations related to genetic findings in osteogenesis imperfecta

    Author : Kristofer Andersson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Osteogenesis imperfecta (OI) is a clinically and genetically heterogeneous connective tissue disorder, mainly caused by mutations in COL1A1 and COL1A2, the genes encoding collagen type I. The cardinal symptoms include bone fragility and varying degrees of growth retardation. READ MORE

  5. 13. Bisphosphonate treatment of children and adolescents with osteogenesis imperfecta : effects on clinical symptoms and bone turnover

    Author : Eva Åström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Osteogenesis imperfecta (OI) is a group of genetic diseases with a wide spectrum of severity, ranging from very mild bone fragility to lethal forms. Without treatment the more severe forms have multiple fractures leading to progressive bone deformities with extreme shortness, frequent skeletal pain and immobilisation. READ MORE

  6. 14. Novel non-collagenous modulators of biomineralization in bone and dentin

    Author : Eszter Somogyi-Ganss; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Calreticulin; nucleobindin; prothrombin; biomineralization; osteogenesis; dentinogenesis;

    Abstract : The formation of mineralized tissues such as bones and teeth is governed on many levels by molecular, genetic, and cellular events to culminate in terminally differentiated cells that secrete a specialized organic matrix, which is later mineralized through the coordinated deposition of calcium phosphate crystals. The formation of this hard tissue phase is tightly regulated by components of the extracellular matrix (ECM), since deviations from this equilibrium result in prevalent, debilitating health problems such as arthritis, vascular calcification, periodontal disease and osteoporosis. READ MORE

  7. 15. Studies on three matrix molecules in bone and dentin

    Author : Ulrika Petersson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Osteoadherin OSAD ; Nucleobindin Nuc ; Calreticulin CRT ; biomineralization; osteogenesis; dentinogenesis;

    Abstract : The biomineralization of bone and dentin is a complex and dynamic process, involving the formation of an organic framework in which mineral crystals are deposited. The noncollagenous proteins (NCPs) of the organic phase play a central role in the extracellular matrix (ECM) organization and mineralization regulation. READ MORE