Search for dissertations about: "ovarian research"

Showing result 1 - 5 of 65 swedish dissertations containing the words ovarian research.

  2. 1. Reproductive physiology of the female three-spined stickleback, Gasterosteus aculeatus

    Author : Chrysoula Roufidou; Bertil Borg; Geir Lasse Taranger; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; overripening of eggs; spawning cycle; brain-pituitary-gonad BPG axis; vitellogenin; ovarian fluid; sex steroids; reproduction; three-spined stickleback; Gasterosteus aculeatus; fish; funktionell zoomorfologi; Functional Zoomorphology;

    Abstract : Reproduction in vertebrates, including fishes, is under control of the brain-pituitary-gonad (BPG) axis. The female three-spined stickleback, Gasterosteus aculeatus, produces egg clutches at intervals of a few days and spawns them in a nest built by male. READ MORE

  4. 2. Hunting a Silent Killer. Biomolecular Approaches in Ovarian Cancer

    Author : Nicolai Arildsen; Bröstcancer-genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ovarian cancer; Molecular biology; genetic variant; TP53 mutation; early detection; Drug Screening Assays; Antitumor; bioinformatics; next generation sequencing; NGS; prognostic and predictive biomarkers; ovarian clear cell cancer; high-grade serous ovarian cancer;

    Abstract : Ovarian cancer is a heterogeneous disease and recent advances in improving patient outcome havebeen limited. It is estimated that a woman’s risk of developing ovarian cancer during her lifetime is about 1 in 70, making it a frequently occurring cancer type in women. READ MORE

  5. 3. Ovarian cancer. Biomarkers, surgical outcome and survival

    Author : Pia Leandersson; Lund Obstetrik och gynekologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; epitelial äggstokscancer; biomarkörer; kirurgi; incidens; överlevnad; epithelial ovarian cancer; biomarkers; ovarian cancer surgery; incidence; survival;

    Abstract : Ovarian cancer is the eighth most common female cancer worldwide and the most lethal of the gynaecologic malignancies. Around 700 women are diagnosed in Sweden per year. Due to vague symptoms most of the patients are diagnosed with late-stage epithelial ovarian cancer (EOC) and prognosis is poor, with a five-year survival of 49%. READ MORE

  6. 4. Endogenous hormones in the etiology of ovarian and endometrial cancers

    Author : Annekatrin Lukanova; Eva Lundin; Pär Stattin; Rudolf Kaaks; Susan E. Hankinson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Public health; ovarian cancer; endometrial cancer; sex-steroid hormones; sex-hormone binding globulin; insulin-like growth factor-I; insulin-like growth factor bidning proteins; C-peptide; Folkhälsomedicin; Public health medicine research areas; Folkhälsomedicinska forskningsområden; epidemiologi; Epidemiology;

    Abstract : The main purpose of this thesis was to examine the relationship of pre-diagnostic circulating levels of sex-steroids (androgens and estrogens), sex hormone binding globuline (SHBG), insulin-like growth factor-I (IGF-I), IGF binding proteins (BP) and C-peptide (as a marker of pancreatic insulin secretion) with risk of ovarian and endometrial cancer. Additionally, the interrelationships of body mass index (BMI), sex-steroids, IGF-I and IGFBP-3 were examined. READ MORE

  7. 5. Intrinsic subtypes and prognostic implications in epithelial ovarian cancer

    Author : Jenny-Maria Jönsson; Bröstcancer-genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ovarian cancer; gene expression profiling; Lynch syndrome; targeted deep sequencing; chromatin remodeling; molecular subtypes; endocrine receptors; prognostic factors; tumor heterogeneity;

    Abstract : Ovarian cancer is the seventh most common cancer in women globally, with approximately 240,000 new cases annually. Although a rare disease, it is the most lethal gynecologic malignancy. Unspecific symptoms result in late diagnosis and a generally poor prognosis. READ MORE