Search for dissertations about: "ovarian-cancer"

Showing result 1 - 5 of 143 swedish dissertations containing the word ovarian-cancer.

  1. 1. Ovarian cancer : Treatment results, prognostic factors, and tumor marker surveillance

    Author : Thomas Högberg; Claes Tropé; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : The total population-based material of 426 ovarian malignancies in the Southeast Health Care Region of Sweden during 1984-1987 was surveyed. It seems that with a program of cytoreductive surgery followed by a cisplatinum chemotherapy combination in the metastasizing cases the overall survival figures have improved. READ MORE

  2. 2. Impact of pregnancies on ovarian cancer : Risk, prognosis and tumor biology

    Author : Camilla Sköld; Ingrid Glimelius; Karin Stålberg; Anthoula Koliadi; Gunilla Enblad; Annika Idahl; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epithelial ovarian cancer; non-epithelial ovarian cancer; reproductive history; parity; risk factor; survival; progesterone receptor;

    Abstract : Ovarian cancer is the most lethal gynecological malignancy. The etiology is complex and not fully understood, partly since ovarian cancer is not one distinct disease, but rather several histologically and clinically different subtypes. READ MORE

  3. 3. Ovarian cancer. Biomarkers, surgical outcome and survival

    Author : Pia Leandersson; Lund Obstetrik och gynekologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; epitelial äggstokscancer; biomarkörer; kirurgi; incidens; överlevnad; epithelial ovarian cancer; biomarkers; ovarian cancer surgery; incidence; survival;

    Abstract : Ovarian cancer is the eighth most common female cancer worldwide and the most lethal of the gynaecologic malignancies. Around 700 women are diagnosed in Sweden per year. Due to vague symptoms most of the patients are diagnosed with late-stage epithelial ovarian cancer (EOC) and prognosis is poor, with a five-year survival of 49%. READ MORE

  4. 4. Hunting a Silent Killer. Biomolecular Approaches in Ovarian Cancer

    Author : Nicolai Arildsen; Bröstcancer-genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ovarian cancer; Molecular biology; genetic variant; TP53 mutation; early detection; Drug Screening Assays; Antitumor; bioinformatics; next generation sequencing; NGS; prognostic and predictive biomarkers; ovarian clear cell cancer; high-grade serous ovarian cancer;

    Abstract : Ovarian cancer is a heterogeneous disease and recent advances in improving patient outcome havebeen limited. It is estimated that a woman’s risk of developing ovarian cancer during her lifetime is about 1 in 70, making it a frequently occurring cancer type in women. READ MORE

  5. 5. Pharmacogenetic Studies of Paclitaxel in Ovarian Cancer : focus on interindividual differences in pharmacodynamics and pharmacokinetics

    Author : Henrik Green; Curt Peterson; Peter Söderkvist; Per Rosenberg; Håkan Melhus; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacogenetics; paclitaxel; LC MS; Taxol; ovarian cancer; pharmacokinetics; CYP2C8; CYP3A4; ABCB1; äggstockscancer; paklitaxel; Clinical pharmacology; Klinisk farmakologi;

    Abstract : Ovarian cancer is one of the most common female cancer diseases in the world today and in Sweden more than 800 new cases are diagnosed every year. The standard treatment consists of chemotherapy with paclitaxel in combination with carboplatin after initial cytoreductive surgery. READ MORE