Search for dissertations about: "oxidative stress, macrophages"

Showing result 1 - 5 of 29 swedish dissertations containing the words oxidative stress, macrophages.

  2. 1. The oxidative stress response of Francisella tularensis

    Author : Marie Honn; Anders Sjöstedt; Helena Lindgren; Andres Melendez; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Francisella tularensis; FupA; MglA; OxyR; ROS; oxidative stress; molekylärbiologi; Molecular Biology;

    Abstract : Francisella tularensis is capable of infecting numerous cell types, including professional phagocytes. Upon phagocytosis, F. tularensis resides within the phagosome before escaping into the cytosol to replicate. Phagocytes constitute a hostile environment rich in ROS, which are employed as a means of killing pathogens. READ MORE

  4. 2. Oxidative stress, macrophages, iron, and atherosclerosis

    Author : Wei Li; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Macrophages have a great capacity to take up exogenous material, such as oxidatively modified low density lipoproteins (oxLDL) and different sources of iron containing structures. OxLDL is taken up into macrophage lysosomes by receptor-mediated endocytosis, but poorly degraded, resulting in foam-cell formation. READ MORE

  5. 3. Oxidative stress in experimental traumatic brain injury

    Author : Mattias Günther; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Traumatic brain injury (TBI) is a leading cause of death and disability among the young population in the industrialized world. The injury consists of immediate damage to the brain tissue, followed by a secondary response involving inflammation and oxidative stress. READ MORE

  6. 4. Altered gene expression in the human airways during oxidative stress

    Author : Tiziana Dandrea; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Nitrogen dioxide; Ozone; Oxidative stress; Gene expression; Redox signalling; GSH; Alveolar macrophages.;

    Abstract : The atmospheric accumulation of pollutant gases, such as N02 and ozone, has been associated with an increased airways hyper-reactivity within the healthy population. Moreover, those with conditions such as asthma and chronic obstructive pulmonary diseases generally experience an exacerbation of their symptoms upon exposure to these noxious gases. READ MORE

  7. 5. Iron and macrophages in atherogenesis

    Author : Xi Ming Yuan; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Oxidation of low density lipoprotein (LDL) may result in its uptake by macrophages and ensuing foam cell formation. Thus, oxidised LDL may play an important role in atherogenesis. Extensive in vitro evidences are in favour of the notion that LDL oxidation by cells present in atherosclerotic plaques requires the presence of transition metals. READ MORE